Evidence map›Paper›PMID 36569594›Full record

ArticleF1000Research2021

Leveraging biochemical reactions to unravel functional impacts of cancer somatic variants affecting protein interaction interfaces.

Francesco Raimondi, Joshua G Burkhart, Matthew J Betts, Robert B Russell, Guanming Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. The landscape of cancer rewired GPCR signaling axes.bioRxiv : the preprint server for biology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Francesco RaimondiBIO@SNS, Scuola Normale Superiore di Pisa, Pisa, Italy, Italy.ORCID 0000-0002-6891-3178
Joshua G BurkhartDivision of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0001-9279-1556
Matthew J BettsHeidelberg University Biochemistry Center, University of Heidelberg, Heidelberg, Germany.
Robert B RussellHeidelberg University Biochemistry Center, University of Heidelberg, Heidelberg, Germany.
Guanming WuDivision of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0001-8196-1177
Heidelberg University · DEOregon Health & Science University · USScuola Normale Superiore · IT

Funding

Reactome - CoreU41HG003751 · NHGRI · ONTARIO INSTITUTE FOR CANCER RESEARCH · PI DEUSTACHIO, PETER G, HERMJAKOB, HENNING · 2012 to 2021
$14.5M
Reactome IDG portal: Pathway-based analysis and visualization of understudied human proteinsU01CA239069 · NCI · OREGON HEALTH & SCIENCE UNIVERSITY · PI DEUSTACHIO, PETER G, STEIN, LINCOLN D. · 2019 to 2021
$1.3M
NCI NIH HHS U01 CA239069NHGRI NIH HHS U41 HG003751
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NeoplasmsHumansMutationProteinsProteomicsSignal TransductionProteinsbiochemical reactionsbiological pathwaysbiological processcancer mutationsnetwork bioinformaticsPPI networkReactomeStructural bioinformaticsvariant interpretation

Identifiers

PMID36569594
PMCPMC9755755.3
OpenAlexW3208551392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.