Evidence map›Paper›PMID 36569199›Full record

ArticleFrontiers in cellular and infection microbiology2022

Outbreak of carbapenem-resistant enterobacteria in a thoracic-oncology unit through clonal and plasmid-mediated transmission of the

Linda Hadjadj, Nadim Cassir, Nadia Saïdani, Clémence Hoffman, Philippe Brouqui, Philippe Astoul, Jean-Marc Rolain, Sophie Alexandra Baron

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Distribution of ST116 carbapenem-resistantFrontiers in cellular and infection microbiology · 2026
    Article
  3. Multiple regional outbreaks caused by global and local VIM-producing Klebsiella pneumoniae clones in Poland, 2006-2019.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  4. Diversification ofMicrobial genomics · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Linda HadjadjAix Marseille Univ, Institut de recherche pour le développement (IRD), Assistance Publique-Hôpitaux de Marseille (APHM), Microbes, Evolution, Phylogénie et Infection (MEPHI), Faculté de Médecine et de Pharmacie, Marseille, France.
Nadim CassirAix Marseille Univ, Institut de recherche pour le développement (IRD), Assistance Publique-Hôpitaux de Marseille (APHM), Microbes, Evolution, Phylogénie et Infection (MEPHI), Faculté de Médecine et de Pharmacie, Marseille, France.
Nadia SaïdaniInstitut hospitalo-universitaire (IHU) Méditerranée Infection, Marseille, France.
Clémence HoffmanInstitut hospitalo-universitaire (IHU) Méditerranée Infection, Marseille, France.
Philippe BrouquiAix Marseille Univ, Institut de recherche pour le développement (IRD), Assistance Publique-Hôpitaux de Marseille (APHM), Microbes, Evolution, Phylogénie et Infection (MEPHI), Faculté de Médecine et de Pharmacie, Marseille, France.
Philippe AstoulDepartment of Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology, North University Hospital, Marseille, France.
Jean-Marc RolainAix Marseille Univ, Institut de recherche pour le développement (IRD), Assistance Publique-Hôpitaux de Marseille (APHM), Microbes, Evolution, Phylogénie et Infection (MEPHI), Faculté de Médecine et de Pharmacie, Marseille, France.
Sophie Alexandra BaronAix Marseille Univ, Institut de recherche pour le développement (IRD), Assistance Publique-Hôpitaux de Marseille (APHM), Microbes, Evolution, Phylogénie et Infection (MEPHI), Faculté de Médecine et de Pharmacie, Marseille, France.
Méditerranée Infection Foundation · FRInstitut de Recherche pour le Développement · FRAix-Marseille Université · FRAssistance Publique Hôpitaux de Marseille · FRCentre Hospitalier de Cornouaille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carbapenemase-producing Objectives: To investigate an outbreak of CPE in a thoracic-oncology unit by using whole genome sequencing (WGS) and to describe the control measures taken to limit the epidemic, including fecal microbiota transplantation (FMT). Methods: A retrospective study between December 2016 and October 2017 was performed to investigate an outbreak of CPE in a thoracic-oncology unit at the North Hospital in Marseille, France. The isolates were identified, and antimicrobial susceptibility tests were performed. All CPE were sequenced using MiSeq and/or MinIon technologies. Nucleotide variations between plasmids and similarity within the same species were investigated. The origin of this outbreak, its spread, and the decolonization of patients in the ward were also studied. Results: Four Conclusions: WGS demonstrated the dissemination of the

Indexed as

Carbapenem-Resistant EnterobacteriaceaeEnterobacteriaceae InfectionsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsDisease OutbreaksEnterobacteriaceaeHumansMicrobial Sensitivity TestsPlasmidsRetrospective StudiesAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsblaOXA-48 genecarbapenemasefecal microbiota transplantationIncL/M plasmidwhole genome sequencing

Identifiers

PMID36569199
PMCPMC9768218
OpenAlexW4311708029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.