Evidence map›Paper›PMID 36569192›Full record

ReviewFrontiers in cellular and infection microbiology2022

Outer membrane vesicles from bacteria: Role and potential value in the pathogenesis of chronic respiratory diseases.

Fei Han, Weiwei Wang, Meng Shi, Hao Zhou, Yiwen Yao, Caiyun Li, Anquan Shang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. EnterohemorrhagicFrontiers in cellular and infection microbiology · 2025
    Article
  6. Review
  7. Protective effect ofMicrobiology spectrum · 2024
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Fei HanDepartment of Laboratory Medicine, The Fourth Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Weiwei WangDepartment of Laboratory Medicine, The Second People's Hospital of Lianyungang & The Oncology Hospitals of Lianyungang, Lianyungang, China.
Meng ShiDepartment of Cardiothoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.
Hao ZhouDepartment of Laboratory Medicine, The Second People's Hospital of Lianyungang & The Oncology Hospitals of Lianyungang, Lianyungang, China.
Yiwen YaoDepartment of Internal Medicine V-Pulmonology, Allergology, Respiratory Intensive Care Medicine, Saarland University Hospital, Homburg, Germany.
Caiyun LiDepartment of Laboratory Medicine, Pukou Branch of Jiangsu People's Hospital & Nanjing Pukou District Central Hospital, Nanjing, China.
Anquan ShangDepartment of Laboratory Medicine, The Second People's Hospital of Lianyungang & The Oncology Hospitals of Lianyungang, Lianyungang, China.
Xian Yang Central Hospital · CNFudan University · CNSaarland University · DESecond Affiliated Hospital of Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases are the leading cause of death in both adults and children, with respiratory infections being the leading cause of death. A growing body of evidence suggests that bacterially released extracellular membrane vesicles play an important role in bacterial pathogenicity by targeting and (de)regulating host cells through the delivery of nucleic acids, proteins, lipids, and carbohydrates. Among the many factors contributing to bacterial pathogenicity are the outer membrane vesicles produced by the bacteria themselves. Bacterial membrane vesicles are being studied in more detail because of their potential role as deleterious mediators in bacterial infections. This review provides an overview of the most current information on the emerging role of bacterial membrane vesicles in the pathophysiology of pneumonia and its complications and their adoption as promising targets for future preventive and therapeutic approaches.

Indexed as

Bacterial InfectionsRespiratory Tract DiseasesBacteriaBacterial Outer Membrane ProteinsChildHumansBacterial Outer Membrane Proteinsbacteriaextracellular vesiclesmechanisms of diseaseouter membrane vesiclesrespiratory tract diseases

Identifiers

PMID36569192
PMCPMC9772277
OpenAlexW4311850412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.