ArticleFrontiers in medicine2022
Application of orthokeratology on myopia control and its effect on ocular surface and meibomian gland function in Chinese myopic adolescents.
Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06023108 (A Single Center,Randomized,Controlled Trial Assessing the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.), which is not on this map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Single Center,Randomized,Controlled Trial Assessing the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.
Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Efficacy of Orthokeratology in Controlling Axial Elongation in Myopic Children and Adolescents: A Systematic Review and Meta-Analysis of Comparative Interventions.Journal of clinical medicine · 2026Review
- One-year effects of orthokeratology lens wear on objective visual quality and corneal densitometry in adolescents with myopia.PloS one · 2026Article
- Three-Year Visual Quality Evaluation in Children Using Orthokeratology Lenses: A Retrospective Study With OPD-Scan III Measurements.Journal of ophthalmology · 2026Article
- Impact of Orthokeratology on Corneal Morphology, Ocular Health and Myopia Control in Children: A 12-Month Clinical Assessment in Myopic Children Living in Kuala Lumpur, Malaysia.Clinical optometry · 2025Article
- Article
- Protective effects of docosahexaenoic acid combined with bilberry extract on myopic Guinea pigs.Frontiers in medicine · 2024Article
- Blinking characteristics analyzed by a deep learning model and the relationship with tear film stability in children with long-term use of orthokeratology.Frontiers in cell and developmental biology · 2024Article
- Short-term application of diquafosol ophthalmic solution benefits children with dry eye wearing orthokeratology lens.Frontiers in medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to investigate the influence of orthokeratology (OK) on myopia control and ocular surface and meibomian gland function in myopic adolescents. Methods: A prospective study was conducted over a 12-month period. The subjects were classified into two groups, namely, the OK lens group and the frame glasses control group. Axial length, corneal curvature, ocular surface, and meibomian gland parameters were measured at baseline, 1, 3, 6, and 12 months after wearing OK lenses. Results: The axial length growth rate in the OK group was significantly slower than in the control group ( Conclusion: These results provide evidence that the use of OK lenses can control the axial growth and progress rate of myopia compared with frame glasses. During the 12-month follow-up, although wearing OK lenses may have aggravated dry eye symptoms, each patient's ocular surface and meibomian gland function did not change significantly, indicating that the use of OK lenses is a relatively safe modality for the control of myopia in adolescents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.