Evidence map›Paper›PMID 36568992›Full record

ArticleWorld journal of clinical cases2022

Multiple myeloma presenting with amyloid arthropathy as the first manifestation: Two case reports.

Chuan He, Xue-Ping Ge, Xiao-Hui Zhang, Ping Chen, Bing-Zong Li

Open access · diamondAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chuan HeDepartment of Haematology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China.
Xue-Ping GeDepartment of Haematology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China.
Xiao-Hui ZhangDepartment of Haematology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China.
Ping ChenDepartment of Haematology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China.
Bing-Zong LiDepartment of Haematology, The Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu Province, China.lbzwz0907@hotmail.com.
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple myeloma (MM) can be accompanied by amyloidosis, which occurs in a small number of patients and is characterized by deposition of light chains in the joints, leading to multiple myeloma-associated amyloid arthropathy (MAA). As a rare complication of MM, clinical manifestations of MAA are often similar to those of rheumatoid arthritis, and the two are easily confused. CASE SUMMARY: In recent years, our center treated two patients of MM with amyloid arthropathy as the first manifestation, both of whom presented with polyarthritis. After treatment for MM, both patients achieved complete remission. However, subsequently, the two patients underwent hip arthroplasty for femoral neck fractures. Congo red staining and immunofluorescence of the joint tissues confirmed MAA after surgery. Eventually, one of the patients died of MM recurrence, while the other survived.

conclusionMAA should be regarded as an initial symptom of MM and should be taken seriously.

Indexed as

AmyloidosisCase reportImmunoglobulin light chain amyloidosisMonoclonal gammopathiesMultiple myelomaPolyarthritis

Identifiers

PMID36568992
PMCPMC9782929
OpenAlexW4311355397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.