Evidence map›Paper›PMID 36568370›Full record

ArticleFrontiers in genetics2022

Studying C-reactive protein and D-dimer levels in blood may prevent severe complications: A study in Bangladeshi COVID-19 patients.

Gazi Nurun Nahar Sultana, Anshika Srivastava, Khalida Akhtaar, Prajjval Pratap Singh, Md Anarul Islam, Rahul Kumar Mishra, Gyaneshwer Chaubey

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Gazi Nurun Nahar SultanaCentre for Advanced Research in Sciences (CARS), Genetic Engineering and Biotechnology Research Laboratory, University of Dhaka, Dhaka, Bangladesh.
Anshika SrivastavaCytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
Khalida AkhtaarCentre for Advanced Research in Sciences (CARS), Genetic Engineering and Biotechnology Research Laboratory, University of Dhaka, Dhaka, Bangladesh.
Prajjval Pratap SinghCytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
Md Anarul IslamCentre for Advanced Research in Sciences (CARS), Genetic Engineering and Biotechnology Research Laboratory, University of Dhaka, Dhaka, Bangladesh.
Rahul Kumar MishraCytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
Gyaneshwer ChaubeyCytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, India.
Banaras Hindu University · INUniversity of Dhaka · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing COVID-19 pandemic has been a scientific, medical and social challenge. Since clinical course of this disease is largely unpredictable and can develop rapidly causing severe complications, it is important to identify laboratory biomarkers, which may help to classify patient's severity during initial stage. Previous studies have suggested C-reactive protein (inflammatory) and D-dimer (biochemical) as an effective biomarker. The differential severity in patients across the world and our limited understanding in the progression of the disease calls for a multi-country analysis for biomarkers. Therefore, we have analyzed these biomarkers among 228 Bangladeshi COVID-19 patients. We observed significant association of COVID-19 severity with these two biomarkers. Thus, we suggest to use these biomarkers for Bangladeshi COVID-19 patients for better disease monitoring. Such validated preventive measures may decrease the case fatality ratio substantially.

Indexed as

BangladeshbiomarkercoronavirusCOVID-19CRP valueD-dimer

Identifiers

PMID36568370
PMCPMC9780378
OpenAlexW4311947324

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.