Evidence map›Paper›PMID 36568335›Full record

ArticleEuropean journal of medicinal chemistry reports2022

Impact of mono- and di-β-galactose moieties in

Mykhaylo Dukh, Joseph Cacaccio, Farukh A Durrani, Ishaan Kumar, Ramona Watson, Walter A Tabaczynski, Penny Joshi, Joseph R Missert, Heinz Baumann, Ravindra K Pandey

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of medicinal chemistry reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mykhaylo DukhPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Joseph CacaccioPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Farukh A DurraniPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Ishaan KumarPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Ramona WatsonPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Walter A TabaczynskiPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Penny JoshiPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Joseph R MissertPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Heinz BaumannMolecular & Cellular Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, 14263, USA.
Ravindra K PandeyPDT Center, Cell Stress Biology, Buffalo, NY, 14263, USA.
Roswell Park Comprehensive Cancer Center · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
StatisticsP01CA055791 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI PANDEY, RAVINDRA K. · 1992 to 2019
$36.0M
NCI NIH HHS P01 CA055791NCI NIH HHS P30 CA016056
6 · The paper itself

Abstract

To investigate the impact of mono- and di-β-galactose moieties in tumor uptake and photodynamic therapy (PDT) efficacy, HPPH [3-(1'-hexyloxy)ethyl-3-devinylpyropheophorobide-a], the meso pyropheophorbide-a [3-ethyl-3-devinyl-pyropheophorbide-a], and the corresponding 20-benzoic acid analogs were used as starting materials. Reaction of the intermediates containing one or two carboxylic acid functionalities with 1-aminogalactose afforded the desired 17

Indexed as

Cancer imagingPhotodynamic therapyPhotosensitizer

Identifiers

PMID36568335
PMCPMC9776133
OpenAlexW4224261658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.