Evidence map›Paper›PMID 36568265›Full record

ArticleCurrent research in pharmacology and drug discovery2022

Down regulation of fatty acid synthase

Abeer M El-Saudi, Miram A Altouhamy, Saad Shaaban, Farid A Badria, Magdy M Youssef, Fardous F El-Senduny

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in pharmacology and drug discovery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Abeer M El-SaudiBiochemistry Division, Chemistry Department, Mansoura University, Mansoura 35516, Egypt.
Miram A AltouhamyBiochemistry Division, Chemistry Department, Mansoura University, Mansoura 35516, Egypt.
Saad ShaabanDepartment of Chemistry, College of Science, King Faisal University, P.O. Box 380, Al-Ahsa, 31982, Saudi Arabia.
Farid A BadriaDepartment of Pharmacognosy, Mansoura University, Mansoura, 35516, Egypt.
Magdy M YoussefBiochemistry Division, Chemistry Department, Mansoura University, Mansoura 35516, Egypt.
Fardous F El-SendunyBiochemistry Division, Chemistry Department, Mansoura University, Mansoura 35516, Egypt.
Mansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) is the 7th most common cancer in women world-wide and the 3rd most common female cancer. For the treatment of OC, there is no successful therapeutic. The medications that are currently available have significant side effects and a low therapeutic index. This work aimed to evaluate the anticancer activity of organoselenium pseudopeptide compound against OC cell lines. After treatment with 50 ​μM of compound

Indexed as

DNA fragmentation MetalloproteniasesLipogenesisOvarian cancerPI3K/AKT/mTORReactive oxygen species

Identifiers

PMID36568265
PMCPMC9780069
OpenAlexW4306770842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.