Evidence map›Paper›PMID 36568064›Full record

ArticleFrontiers in endocrinology2022

Clinical outcome analysis of frozen-thawed embryo transfer on Day 7.

Xinmi Liu, Hua Lou, Junwei Zhang, Mingze Du, Yulin Du, Shanshan Wu, Yichun Guan, Jing Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. A review of artificial intelligence applications in in vitro fertilization.Journal of assisted reproduction and genetics · 2025
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xinmi LiuReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Hua LouReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Junwei ZhangReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Mingze DuReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yulin DuReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shanshan WuReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yichun GuanReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jing LiuReproductive Medicine Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Third Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the clinical outcomes of Day 7 (D7) frozen-thawed embryo transfer (FET) and to provide a reference value for clinical work. Methods: This was a retrospective cohort study. Patients undergoing FET cycles in the Reproductive Medicine Center of the Third Affiliated Hospital of Zhengzhou University between December 2015 and January 2021 were included. According to the developmental stage of the embryos at transfer, the embryos were divided into three groups: Day (D) 5, D6 and D7 blastocysts. Group D7 was compared with Groups D5 and D6. Simultaneously, the preimplantation genetic testing (PGT) and non-PGT cycles in Group D7 were analyzed and compared. The main outcomes were the clinical pregnancy, live birth and miscarriage rates. The secondary outcomes were the implantation and euploidy rates. Results: In total, 5945, 4094 and 137 FET cycles were included in the D5, D6 and D7 groups, respectively. The clinical pregnancy rate was significantly lower in Group D7 than in Groups D5 (13.9% vs 62.9%, Conclusions: D7 blastocyst transfer can yield a live birth rate that is lower than that for D5 and D6 blastocysts but has value for transfer. PGT for D7 blastocysts may reduce the number of ineffective transfers and improve the outcome of D7 blastocyst transfer, which can be performed according to a patient's situation.

Indexed as

Abortion, SpontaneousEmbryo ImplantationEmbryo TransferFemaleHumansPregnancyPregnancy RateRetrospective Studiesabortionclinical pregnancyD7euploidFETlive birth

Identifiers

PMID36568064
PMCPMC9780262
OpenAlexW4311947925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.