Evidence map›Paper›PMID 36568051›Full record

ArticleJournal of advanced pharmaceutical technology & research

Aniek Setiya Budiatin, Maria Apriliani Gani, Bulan Rhea Kaulika Hadinar Putri, Samirah Samirah, Dyah Hikmawati, Alfian Pramudita Putra, Nily Su'aidah, Junaidi Khotib

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced pharmaceutical technology & research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aniek Setiya BudiatinDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Maria Apriliani GaniDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Bulan Rhea Kaulika Hadinar PutriDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Samirah SamirahDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Dyah HikmawatiDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Alfian Pramudita PutraDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Nily Su'aidahDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Junaidi KhotibDepartment of Pharmacy Practice, Faculty of Pharmacy, Airlangga University, Surabaya, Indonesia.
Airlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The injectable bone substitute (IBS) is a self-setting local drug delivery system that adjusts the shape of the bone gap in the fracture. This study aimed to examine the effectiveness of IBS composites of bovine hydroxyapatite (BHA) and alendronate (Ale) in accelerating bone growth in osteoporotic rats. IBS was made by mixing BHA with gelatin 5%, hydroxypropyl methylcellulose (HPMC) 2%, and Ale 10%. The physical properties of IBS were viscosity, injectability, and density tests. Twenty-four female Wistar rats were divided into four groups. After 8 weeks, 2 mm gap was made in the right femur of all rats and filled with IBS. The healing process was observed after 6 weeks with X-ray imaging and H and E staining. The obtained results showed viscosity, injectability, and density value of IBS from 30.4 to 39.4 dPa.s, 98.22%-98.64%, and 0.6325-0.8409 g/cm

Indexed as

Alendronatebovine hydroxyapatitefractureinjectable bone substituteosteoporosis

Identifiers

PMID36568051
PMCPMC9784046
OpenAlexW4312210150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.