Evidence map›Paper›PMID 36567803›Full record

ArticleOncoimmunology2023

BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded

Gloria Esteso, María José Felgueres, Álvaro F García-Jiménez, Christina Reyburn-Valés, Alberto Benguría, Enrique Vázquez, Hugh T Reyburn, Nacho Aguiló, Carlos Martín, Eugenia Puentes and 3 more

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. γδ T cells and cancer.The Journal of clinical investigation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Gloria EstesoDepartment of Immunology and Oncology, National Centre for Biotechnology, Spanish National Research Council, Madrid, Spain.
María José FelgueresDepartment of Immunology and Oncology, National Centre for Biotechnology, Spanish National Research Council, Madrid, Spain.
Álvaro F García-JiménezDepartment of Immunology and Oncology, National Centre for Biotechnology, Spanish National Research Council, Madrid, Spain.
Christina Reyburn-ValésDepartment of Immunology and Oncology, National Centre for Biotechnology, Spanish National Research Council, Madrid, Spain.
Alberto BenguríaServicio de Genómica, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Enrique VázquezServicio de Genómica, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
Hugh T ReyburnDepartment of Immunology and Oncology, National Centre for Biotechnology, Spanish National Research Council, Madrid, Spain.
Nacho AguilóGrupo de Genética de Micobacterias, Departamento de Microbiología y Medicina Preventiva, Facultad de Medicina, Universidad de Zaragoza, IIS-Aragon; Zaragoza, Spain and CIBER Enfermedades Respiratorias, Instituto de Salud Carlos III; Madrid, Spain.
Carlos MartínGrupo de Genética de Micobacterias, Departamento de Microbiología y Medicina Preventiva, Facultad de Medicina, Universidad de Zaragoza, IIS-Aragon; Zaragoza, Spain and CIBER Enfermedades Respiratorias, Instituto de Salud Carlos III; Madrid, Spain.
Eugenia PuentesClinical Research Department y Research & Development Department, Biofabri, Grupo Zendal, O'Porriño, Pontevedra, Spain.
Ingrid MurilloClinical Research Department y Research & Development Department, Biofabri, Grupo Zendal, O'Porriño, Pontevedra, Spain.
Esteban RodríguezClinical Research Department y Research & Development Department, Biofabri, Grupo Zendal, O'Porriño, Pontevedra, Spain.
Mar Valés-GómezDepartment of Immunology and Oncology, National Centre for Biotechnology, Spanish National Research Council, Madrid, Spain.ORCID 0000-0001-7424-3206
Consejo Superior de Investigaciones Científicas · ESSpanish National Centre for Cardiovascular Research · ESUniversidad de Zaragoza · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacillus Calmette-Guérin (BCG), the nonpathogenic

Indexed as

Antineoplastic AgentsMycobacterium bovisUrinary Bladder NeoplasmsBCG VaccineHumansKiller Cells, NaturalLeukocytes, MononuclearT-LymphocytesAntineoplastic AgentsBCG VaccineBCGbladder cancerCancer immunologygamma delta T lymphocytesimmunotherapyNK activation

Identifiers

PMID36567803
PMCPMC9788708
OpenAlexW4312192600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.