Evidence map›Paper›PMID 36567656›Full record

ArticleDevelopmental psychobiology2023

Maternal prenatal cortisol and the interaction of income and pre-pregnancy body mass index are independently associated with newborn cortisol.

Brie M Reid, Natasha Sokol, Nicki L Aubuchon-Endsley, Laura R Stroud

Open access · greenAbstract read
In one paragraph

Article in Developmental psychobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Brie M ReidDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Natasha SokolDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Nicki L Aubuchon-EndsleyDepartment of Psychology, The University of Tulsa, Tulsa, Oklahoma, USA.
Laura R StroudDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.
Brown University · USMiriam Hospital · USUniversity of Tulsa · US

Funding

Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI KayLoni L. Olson · 2021 to 2026
$14.6M
ALCOHOL INTERVENTION/TREATMENT OUTCOME RESEARCH TRAININGT32AA007459 · NIAAA · BROWN UNIVERSITY · PI ROBERT MIRANDA, PETER M. MONTI · 1986 to 2026
$13.3M
Prenatal marijuana: Impact on infant neurobehavior, stress, & epigenetic mechanismsR01DA044504 · NIDA · MIRIAM HOSPITAL · PI STROUD, LAURA R · 2017 to 2021
$3.5M
Maternal Depression Placental HPA Regulation & Fetal-Neonatal Stress ResponseR01MH079153 · NIMH · MIRIAM HOSPITAL · PI STROUD, LAURA R · 2007 to 2011
$3.2M
Research Training in Childhood Stress, Trauma, and ResilienceT32HD101392 · NICHD · MIRIAM HOSPITAL · PI PARADE, STEPHANIE HART, STROUD, LAURA R · 2020 to 2024
$1.7M
The Effect of Antenatal Maternal Cannabis Use on Parenting BehaviorK01DA054324 · NIDA · MIRIAM HOSPITAL · PI Natasha Alessandra Sokol · 2022 to 2026
$931k
Machine learning methods to assess risk for prenatal and neonatal iron deficiency anemia from maternal stress exposureK99HD109373 · NICHD · MIRIAM HOSPITAL · PI REID, BRIE M · 2022 to 2023
$254k
NIAAA NIH HHS T32 AA007459NIAAA NIH HHS T32AA007459NICHD NIH HHS K99 HD109373NICHD NIH HHS T32 HD101392NIDA NIH HHS 5R01DA044504NIDA NIH HHS K01 DA054324NIDA NIH HHS R01 DA044504NIGMS NIH HHS 1P20GM139767NIGMS NIH HHS P20 GM139767NIMH NIH HHS R01 MH079153NIMH NIH HHS R01MH079153
6 · The paper itself

Abstract

While extensive research has supported the developmental programming hypothesis regarding contributions of prenatal psychosocial or nutritional adversity to offspring stress physiology, fewer studies consider both exposures together with maternal stress physiology. This study examined newborn cortisol output during a stressor as a function of maternal pre-pregnancy health status and nutritional history (pre-pregnancy body mass index [PPBMI]), economic resources (household income), and maternal cortisol awakening response (mCAR) in late pregnancy. Participants were 102 mother-infant pairs from an economically and racial/ethnically diverse sample. Offspring salivary cortisol response to a neurobehavioral exam was assessed at 1 month. Income and maternal PPBMI were positively associated with mCAR in late pregnancy. mCAR was positively related to 1-month newborn cortisol response. The interaction of income and PPBMI was positively associated with newborn cortisol output during an exam at 1-month. Mothers with the highest PPBMI and lowest income had offspring with higher cortisol responses than offspring of mothers with higher income and lower PPBMI. There was no evidence of indirect mediation effects of predictors (PPBMI, income, and interaction) on infant cortisol via mCAR. The differential effects of the interaction of PPBMI and income suggest that these exposures influence infant cortisol output in the context of one another, independent of maternal pregnancy cortisol.

Indexed as

HydrocortisonePrenatal Exposure Delayed EffectsBody Mass IndexFemaleHumansInfantInfant, NewbornMothersPovertyPregnancyStress, PsychologicalHydrocortisonecortisolincomenewbornpregnancystressweight

Identifiers

PMID36567656
PMCPMC9940703
OpenAlexW4312210514

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.