Evidence map›Paper›PMID 36567164›Full record

Observational studyAnais brasileiros de dermatologia

Did COVID-19 lockdown delay actually worsen melanoma prognosis?

Pedro Gil-Pallares, Olalla Figueroa-Silva, Maria Eugenia Gil-Pallares, José Ángel Vázquez-Bueno, Francisca Piñeyro-Molina, Benigno Monteagudo, Cristina De Las Heras-Sotos

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pedro Gil-PallaresDepartment of Dermatology, Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain. Electronic address: pedrogilpallares@gmail.com.
Olalla Figueroa-SilvaDepartment of Dermatology, Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain.
Maria Eugenia Gil-PallaresUniversidad de Santiago de Compostela, Santiago de Compostela, Spain.
José Ángel Vázquez-BuenoDepartment of Pathology, Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain.
Francisca Piñeyro-MolinaDepartment of Dermatology, Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain.
Benigno MonteagudoDepartment of Dermatology, Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain.
Cristina De Las Heras-SotosDepartment of Dermatology, Complejo Hospitalario Universitario de Ferrol, Ferrol, Spain.
Complejo Hospitalario Universitario de Ferrol · ESUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 lockdown possibly meant a delay in the diagnosis and treatment of melanoma and therefore, worsening its prognosis. This unique situation of diagnosis deferral is an exceptional opportunity to investigate melanoma biology.

objectivesTo evaluate the immediate and mid-term impact of diagnosis delay on melanoma.

methodsA retrospective observational study of melanoma diagnosed between March 14

resultsA total of 119 melanomas were diagnosed. There were no differences in age, sex, incidence, location, presence of ulceration or mitoses, and in situ/invasive melanoma rate (p>0.05). After the recovery of the normal activity, Breslow thickness increased in comparison with the previous year (2.4 vs 1.9mm, p<0.05) resulting in a significant upstaging according to the AJCC 8 STUDY LIMITATIONS: The main limitation is that this is a single-center study.

conclusionsThe COVID-19 lockdown implied a diagnosis delay leading to a mid-term increase in Breslow thickness and an upstaging of invasive melanomas. However, the detection deferral did not result in a higher progression of in situ to invasive melanoma, in our sample.

Indexed as

COVID-19MelanomaSkin NeoplasmsCommunicable Disease ControlCutaneous Malignant MelanomaHumansPrognosisRetrospective StudiesCOVID-19MelanomaPrognosisQuarantineSARS-CoV-2

Identifiers

PMID36567164
PMCPMC9729652
OpenAlexW4311095132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.