Evidence map›Paper›PMID 36567064›Full record

SynthesisIndian heart journal

Prevalence of sarcopenia in heart failure: A systematic review.

Lakshman Chandrashekhar Iyer, K Vaishali, Abraham Samuel Babu

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05878106 (Creatine Supplementation and Resistance Training in Patients With Breast Cancer), which is not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05878106 naunknown statusnot on this map

Creatine Supplementation and Resistance Training in Patients With Breast Cancer (CaRTiC Study)

TypeinterventionalSponsorUniversity of DeustoRan2024 to 2025Enrolled120ConditionsBreast Cancer, Supplementation, Resistance Training, Physical PerformanceArmsCreatine supplementation, Resistance training
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Impact of heart failure on skeletal muscle: an overview.Journal of geriatric cardiology : JGC · 2026
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  6. Article
  7. Review
  8. Article
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  11. Article
  12. Article
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  14. Observational
  15. Article
  16. Review
  17. Observational
  18. Review
  19. Impact of sodium-glucose cotransporter-2 inhibitor use on peak VOFrontiers in cardiovascular medicine · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lakshman Chandrashekhar IyerDepartment of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India; MGM College of Physiotherapy, Sector 30, Navi Mumbai, Maharashtra, India.
K VaishaliDepartment of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Abraham Samuel BabuDepartment of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: abraham.babu@manipal.edu.
Manipal Academy of Higher Education · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHeart Failure (HF) is emerging as a crucial factor promoting muscle wasting and dysfunction contributing to sarcopenia. This modulates disease severity and reduces exercise capacity and leading to poorer outcomes. Therefore, we aimed to systematically investigate the overall prevalence of sarcopenia in HF.

methodsAn electronic search was carried out in selected databases until 21st January, 2021. Data was pooled from the included articles and represented as pooled prevalence of sarcopenia. Subgroup analysis was undertaken between methods of diagnosis of sarcopenia, gender, ejection fraction, median time point and geographical region.

resultsAmongst 32,643 citations imported from selected databases, 12 articles were included in final analysis. Analysis for prevalence of sarcopenia was 34%, with prevalence rates ranging from 10.1% to 68%. Subgroup analysis revealed strong associations between Dual-energy X-ray Absorptiometry (DXA) and Asian Working Group for Sarcopenia (AWGS) (chi square = 3.24; p < 0.001), with a good level of agreement (kappa = 0.76 [95% CI: 0.70-0.82]; p < 0.001). Gender wise analysis revealed higher prevalence of sarcopenia among males (66%) than females (34%).

conclusionSarcopenia is highly prevalent among those with HF (irrespective of type of HF) and is more commonly seen in males compared to females.

Indexed as

Heart FailureSarcopeniaAbsorptiometry, PhotonFemaleHumansMaleMuscle, SkeletalPrevalenceHeart failureMuscle wastingPrevalenceSarcopenia

Identifiers

PMID36567064
PMCPMC9986732
OpenAlexW4312221522

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.