ReviewBreast cancer research and treatment2023
Bioimpedance spectroscopy for breast cancer-related lymphedema assessment: clinical practice guidelines.
Review in Breast cancer research and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07011316 (Subclinical Assessment and Monitoring of Lymphatic System Function in Oncology Patients as Part of Physiotherapeutic Prevention of Limb Lymphoedema), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Subclinical Assessment and Monitoring of Lymphatic System Function in Oncology Patients as Part of Physiotherapeutic Prevention of Limb Lymphoedema
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- [Integrated care for long-responder women with metastatic breast cancer: Expert opinion for long term management in spain].Atencion primaria · 2026Guideline
- Bioimpedance Measurement for Monitoring Chronic Wounds: A Systematic Review.International wound journal · 2025Pooled it
- The impact of online-delivered controlled physical activity on cardiorespiratory fitness and heart rate variability in breast cancer survivors.Scientific reports · 2026Trial
- The Importance of a Pre-treatment Baseline When Screening Patients for Breast-Cancer-Related Lymphedema.Annals of surgical oncology · 2025Trial
- Based on the health belief model: a qualitative exploration of factors influencing early screening behavior for breast cancer-related lymphedema.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Breast cancer-related lymphoedema: approach and management.Singapore medical journal · 2026Article
- Multimodal Assessment of Breast Cancer-Related Lymphedema Using Bioimpedance Analysis, Ultrasound Tissue Thickness, and Shear Wave Elastography.Diagnostics (Basel, Switzerland) · 2026Article
- Remote Monitoring of Bioelectrical Impedance in Patients With Breast Cancer-Related Lymphedema: 1-Year Pilot Longitudinal Study.JMIR biomedical engineering · 2026Article
- Layer-Specific Assessment of Dermal Thickness and Stiffness Using Shear Wave Elastography in Gynecologic Cancer-Related Lower-Limb Lymphedema: An Exploratory Cross-Sectional Study.International journal of general medicine · 2026Article
- Breast cancer-related lymphedema of the upper limb: integrating early surveillance and functional surgery into a synergistic management paradigm.Frontiers in surgery · 2026Review
- Characterizing Trends of Lymphedema After Axillary Lymph Node Dissection with and Without Immediate Lymphatic Reconstruction.Cancers · 2025Article
- Use of membrane lipidome, body weight, and composition in stratification of early breast cancer patients.NPJ breast cancer · 2025Article
- Robot-Assisted Lymph Node-to-Vein Anastomosis: Lessons from the First 22 Cases at a High-Volume Lymphatic Supermicrosurgery Center.Current oncology (Toronto, Ont.) · 2025Article
- Article
- Clinical Relevance of Animal Models of Lymphatic Dysfunction and Lymphedema.Microcirculation (New York, N.Y. : 1994) · 2025Review
- Imaging and management of lymphedema in the era of precision oncology.The British journal of radiology · 2025Review
- Evaluation of response to treatment in breast cancer-related lymphedema.Turkish journal of physical medicine and rehabilitation · 2025Article
- Novel bioparameters derived from bioimpedance measurements for accurate prediction of weight status in infant-juvenile individuals: A regression analysis.Journal of electrical bioimpedance · 2025Article
- Machine learning-based personalized risk prediction model for breast cancer-related lymphedema after surgery.Frontiers in oncology · 2025Article
- Short- and Long-Term Efficacy of Hyperbaric Oxygen Therapy in Irradiated Breast Cancer Patients With Long-Standing Lymphedema: A Prospective Case Series.Cancer reports (Hoboken, N.J.) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBreast cancer-related lymphedema (BCRL) represents a significant concern for patients following breast cancer treatment, and assessment for BCRL represents a key component of survivorship efforts. Growing data has demonstrated the benefits of early detection and treatment of BCRL. Traditional diagnostic modalities are less able to detect reversible subclinical BCRL while newer techniques such as bioimpedance spectroscopy (BIS) have shown the ability to detect subclinical BCRL, allowing for early intervention and low rates of chronic BCRL with level I evidence. We present updated clinical practice guidelines for BIS utilization to assess for BCRL. METHODS AND
resultsReview of the literature identified a randomized controlled trial and other published data which form the basis for the recommendations made. The final results of the PREVENT trial, with 3-year follow-up, demonstrated an absolute reduction of 11.3% and relative reduction of 59% in chronic BCRL (through utilization of compression garment therapy) with BIS as compared to tape measurement. This is in keeping with real-world data demonstrating the effectiveness of BIS in a prospective surveillance model. For optimal outcomes patients should receive an initial pre-treatment measurement and subsequently be followed at a minimum quarterly for first 3 years then biannually for years 4-5, then annually as appropriate, consistent with previous guidelines; the target for intervention has been changed from a change in L-Dex of 10 to 6.5. The lack of pre-operative measure does not preclude inclusion in the prospective surveillance model of care.
conclusionThe updated clinical practice guidelines present a standardized approach for a prospective model of care using BIS for BCRL assessment and supported by evidence from a randomized controlled trial as well as real-world data.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.