Evidence map›Paper›PMID 36566266›Full record

ArticleClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023

SARS-CoV-2 infection in patients with melanoma: results of the Spanish Melanoma Group registry.

Maria Gonzalez-Cao, Teresa Puertolas, Clara Martinez-Vila, Cristina Carrera, Cayetana Maldonado Seral, Pedro Rodríguez-Jiménez, Silvia Sequero, Pablo Cerezuela-Fuentes, Rosa Feltes Ochoa, Eva Muñoz and 31 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04344002 (Observational Retrospective Register of Spanish Lung and Melanoma Cancer Patients With COVID19 Disease), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04344002 completednot on this map

Observational Retrospective Register of Spanish Lung and Melanoma Cancer Patients With COVID19 Disease

Typeobservational_patient_registrySponsorSpanish Lung Cancer GroupRan2020 to 2021Enrolled886ConditionsCovid-19, Lung Cancer
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors at 20 institutions in 1 country.

Maria Gonzalez-CaoTranslational Cancer Research Unit, Instituto Oncologico Dr Rosell, Dexeus University Hospital, C/Sabino Arana, 5, 080028, Barcelona, Spain. mgonzalezcao@oncorosell.com.ORCID http://orcid.org/0000-0003-3791-540X
Teresa PuertolasMedical Oncology Department, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Clara Martinez-VilaFundación Althaia, Xarxa Assistencial Universitària de Manresa, Barcelona, Spain.
Cristina CarreraDermatology Department, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Melanoma Group IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Cayetana Maldonado SeralHospital Universitario Central de Asturias, Oviedo, Spain.
Pedro Rodríguez-JiménezDermatology Department, Hospital Universitario la Princesa, Madrid, Spain.
Silvia SequeroMedical Oncology Department, Hospital San Cecilio, Granada, Spain.
Pablo Cerezuela-FuentesMedical Oncology Department, Hospital Clinico Universitario Virgen Arrixaca, Murcia, Spain.
Rosa Feltes OchoaHospital Universitario la Paz, Madrid, Spain.
Eva MuñozMedical Oncology Department. Hospital, Universitari Vall d'Hebron, Barcelona, Spain.
Mónica Antoñanzas BasaMedical Oncology Department, Hospital Clinico San Carlos, Madrid, Spain.
Juan Martín-LiberalMedical Oncology Department, Catalan Institute of Oncology (ICO) Hospitalet, Barcelona, Spain.
Ainara SoriaMedical Oncology Department, Hospital Ramon y Cajal, Madrid, Spain.
Juan Francisco Rodriguez MorenoMedical Oncology Department, Centro Integral Oncologico HM Clara Campal, Madrid, Spain.
Ivan Marquez-RodasMedical Oncology Department, Hospital General Universitario Gregorio Marañon and CIBERONC, Madrid, Spain.
Pilar Lopez CriadoMedical Oncology Department, Hospital MD Anderson, Madrid, Spain.
José Luis ManzanoMedical Oncology Department, Catalonian Institute of Oncology (ICO-Badalona), Germans Trias i Pujol Research Institute and Hospital (IGTP), Badalona, Barcelona, Spain.
Rafael Lopez-CastroMedical Oncology Department, HCU Valladolid, Valladolid, Spain.
Pablo Ayala de MiguelHospital San Pedro de Alcántara, Cáceres, Spain.
Laura VillalobosHospital Principe de Asturias, Alcala de Henares, Spain.
Salvador Martin AlgarraMedical Oncology Department, Clinica Universitaria de Navarra, Pamplona, Spain.
Ines Gonzalez-BarralloHospital Clinico de Valencia, Valencia, Spain.
Aram BoadaDermatology Department, Hospital Germans Trias i Pujol Research Institute and Hospital (IGTP), Badalona, Barcelona, Spain.
Almudena García CastañoMedical Oncology Department, Hospital Marqués de Valdecilla, Santander, Spain.
Susana PuigDermatology Department, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Melanoma Group IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Guillermo CrespoHospital Universitario de Burgos, Burgos, Spain.
Pablo Luna FraHospital Son Espases, Mallorca, Spain.
Cristina Aguayo ZamoraHospital Universitario Infanta Sofía, Madrid, Spain.
Marta Feito RodríguezHospital Universitario la Paz, Madrid, Spain.
Lara VallesHospital General de Villalba, Madrid, Spain.
Ana DrozdowskyjTranslational Cancer Research Unit, Instituto Oncologico Dr Rosell, Dexeus University Hospital, C/Sabino Arana, 5, 080028, Barcelona, Spain.
Jesús GardeazabalHospital de Cruces, Bilbao, Spain.
Luis Antonio Fernandez-MoralesHospital Parc Tauli, Sabadell, Spain.
Alberto RodrigoHospital Arnau de Vilanova, Lleida, Spain.
Raquel CruzHospital Universitario Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain.
Oriol YelamosDermatology Department, Hospital Sant Pau, Barcelona, Spain.
Belen RubioOncology Department, Hospital Quiron, Madrid, Spain.
Karmele MujicaHospital Donostia, Donostia, Spain.
Mariano ProvencioHospital Puerta de Hierro, Madrid, Spain.
Alfonso BerrocalHospital Universitario General de Valencia, Valencia, Spain.
Spanish Melanoma Group (GEM)
Centre for Biomedical Network Research on Rare Diseases · ESHospital Universitario La Paz · ESInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol · ESInstituto Oncológico Dr. Rosell · ESAlthaia · ESClinica Universidad de Navarra · ESDeleted InstitutionHM Hospitales · ESHospital Arnau de Vilanova · ESHospital Clínico San Carlos · ESHospital Clínico Universitario de Valencia · ESHospital de Cruces · ESHospital de Sant Pau · ESHospital General Universitario De Valencia · ESHospital General Universitario Gregorio Marañón · ESHospital San Pedro de Alcántara · ESHospital Universitario Central de Asturias · ESHospital Universitario de Burgos · ESHospital Universitario de La Princesa · ESHospital Universitario Infanta Sofía · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Spanish Melanoma Group (GEM) developed a national registry of patients with melanoma infected by SARS-CoV-2 ("GRAVID").

methodsThe main objective was to describe the COVID-19 fatality rate in patients with melanoma throughout the pandemic, as well as to explore the effect of melanoma treatment and tumor stage on the risk of COVID-19 complications. These are the final data of the register, including cases from February 2020 to September 2021.

resultsOne hundred-fifty cases were registered. Median age was 68 years (range 6-95), 61 (40%) patients were females, and 63 (42%) patients had stage IV. Thirty-nine (26%) were on treatment with immunotherapy, and 17 (11%) with BRAF-MEK inhibitors. COVID-19 was resolved in 119 cases, including 85 (57%) patients cured, 15 (10%) that died due to melanoma, and 20 (13%) that died due to COVID-19. Only age over 60 years, cardiovascular disorders, and diabetes mellitus increased the risk of death due to COVID-19, but not advanced melanoma stage nor melanoma systemic therapies. Three waves have been covered by the register: February-May 2020, August-November 2020, and December 2020-April 2021. The first wave had the highest number of registered cases and COVID-19 mortality.

conclusionTumor stage or melanoma treatments are non-significant prognostic factors for COVID-19 mortality. During the pandemic in Spain there was a downward trend in the number of patients registered across the waves, as well as in the severity of the infection. CLINICALTRIALS: GOV IDENTIFIER: NCT04344002.

Indexed as

COVID-19Diabetes MellitusMelanomaAdolescentAdultAgedAged, 80 and overChildFemaleHumansMaleMiddle AgedRegistriesSARS-CoV-2Young AdultCancerCOVID-19ImmunotherapyMelanomaPD-1

Identifiers

PMID36566266
PMCPMC9789885
OpenAlexW4312204940

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.