ArticleVirchows Archiv : an international journal of pathology2023
Application of postmortem imaging modalities in cases of sudden death due to cardiovascular diseases-current achievements and limitations from a pathology perspective : Endorsed by the Association for European Cardiovascular Pathology and by the International Society of Forensic Radiology and Imaging.
Article in Virchows Archiv : an international journal of pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- The Role of Cardiac Troponins in Postmortem Diagnosis of Myocardial Ischemia: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- The Z-scores of cardiac indices among healthy children: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Multidisciplinary and Personalized Molecular Diagnosis to Solving Sudden Death During Sport.Molecular diagnosis & therapy · 2026Review
- Redefining the Post-Mortem Investigation of Sudden Cardiac Death: Systematic Cardiac MR with Macroscopic and Histological Correlation from the Friuli Venezia Giulia Regional Registry.Diagnostics (Basel, Switzerland) · 2026Article
- Multiphase post-mortem CT angiography (MPMCTA) in sudden natural death: diagnostic contribution and workflow impact in a forensic autopsy series.Forensic science, medicine, and pathology · 2026Article
- Histological artifacts induced by the contrast agent in Multi-Phase Post-Mortem CT Angiography (MPMCTA): Part I - Normal Tissues.Forensic science, medicine, and pathology · 2026Article
- Histological artifacts induced by the contrast agent in multi-phase post-mortem CT angiography (MPMCTA): Part II - Pathological tissues.Forensic science, medicine, and pathology · 2026Article
- Post-mortem cardiac-specific troponin-I (cTnI) to determine the cause of non-traumatic hemopericardium.Forensic science, medicine, and pathology · 2026Article
- Post-mortem ultrasound study of coronary circulation on ex-situ hearts.International journal of legal medicine · 2026Article
- Article
- Ischemic and non-ischemic myocardial injuries at autopsy- an overview for forensic pathologists.International journal of legal medicine · 2025Review
- The current state of forensic imaging - post mortem imaging.International journal of legal medicine · 2025Review
- Ultrasound imaging identifies the antemortem and postmortem features: PMI in euthanized dogs with an implication of cause of death may mask the imaging findings.Open veterinary journal · 2025Article
- The evolution of postmortem investigation: a historical perspective on autopsy's decline and imaging's role in its revival.Frontiers in radiology · 2025Article
- Post-mortem Cardiac MRI in Sudden Cardiac Death: The Interesting Intertwining of Radiology and Histology to Diagnose Arrhythmic Death or Myocardial Infarction.Current medical imaging · 2025Article
- High-risk coronary plaque of sudden cardiac death victims: postmortem CT angiographic features and histopathologic findings.International journal of legal medicine · 2024Article
- Postmortem magnetic resonance imaging findings of tricuspid atresia with ventricular and atrial septal defects and subvalvular pulmonic stenosis in a Japanese native Noma horse.Journal of equine science · 2023Article
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Authors and funding
15 authors at 9 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postmortem imaging (PMI) is increasingly used in postmortem practice and is considered a potential alternative to a conventional autopsy, particularly in case of sudden cardiac deaths (SCD). In 2017, the Association for European Cardiovascular Pathology (AECVP) published guidelines on how to perform an autopsy in such cases, which is still considered the gold standard, but the diagnostic value of PMI herein was not analyzed in detail. At present, significant progress has been made in the PMI diagnosis of acute ischemic heart disease, the most important cause of SCD, while the introduction of postmortem CT angiography (PMCTA) has improved the visualization of several parameters of coronary artery pathology that can support a diagnosis of SCD. Postmortem magnetic resonance (PMMR) allows the detection of acute myocardial injury-related edema. However, PMI has limitations when compared to clinical imaging, which severely impacts the postmortem diagnosis of myocardial injuries (ischemic versus non-ischemic), the age-dating of coronary occlusion (acute versus old), other potentially SCD-related cardiac lesions (e.g., the distinctive morphologies of cardiomyopathies), aortic diseases underlying dissection or rupture, or pulmonary embolism. In these instances, PMI cannot replace a histopathological examination for a final diagnosis. Emerging minimally invasive techniques at PMI such as image-guided biopsies of the myocardium or the aorta, provide promising results that warrant further investigations. The rapid developments in the field of postmortem imaging imply that the diagnosis of sudden death due to cardiovascular diseases will soon require detailed knowledge of both postmortem radiology and of pathology.
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