Evidence map›Paper›PMID 36565200›Full record

SynthesisJournal of the American Heart Association2023

Ross Procedure Versus Mechanical Versus Bioprosthetic Aortic Valve Replacement: A Network Meta-Analysis.

Yujiro Yokoyama, Toshiki Kuno, Nana Toyoda, Tomohiro Fujisaki, Hisato Takagi, Shinobu Itagaki, Michael Ibrahim, Maral Ouzounian, Ismail El-Hamamsy, Shinichi Fukuhara

Open access · goldAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 59 citations in OpenAlex.

  1. Five-year results from a prospective, single-arm European trial on decellularized allografts for aortic valve replacement-the ARISE Study and ARISE Registry Data.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024
    Trial
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  17. Protected Ross technique.JTCVS techniques · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Yujiro YokoyamaDepartment of Surgery St. Luke's University Health Network Bethlehem PA.ORCID 0000-0001-8552-9496
Toshiki KunoDepartment of Cardiology, Montefiore Medical Center Albert Einstein College of Medicine New York NY.ORCID 0000-0002-2487-8366
Nana ToyodaDepartment of Cardiovascular Surgery Icahn School of Medicine at Mount Sinai New York NY.
Tomohiro FujisakiDepartment of Medicine Icahn School of Medicine at Mount Sinai, Mount Sinai Morningside and West New York NY.ORCID 0000-0001-9204-8551
Hisato TakagiDepartment of Cardiovascular Surgery Shizuoka Medical Center Shizuoka Japan.ORCID 0000-0002-5594-8072
Shinobu ItagakiDepartment of Cardiovascular Surgery Icahn School of Medicine at Mount Sinai New York NY.
Michael IbrahimDivision of Cardiovascular Surgery Hospital of the University of Pennsylvania Philadelphia PA.
Maral OuzounianDivision of Cardiovascular Surgery Peter Munk Cardiac Centre, Toronto General Hospital and the University of Toronto, Toronto Ontario Canada.
Ismail El-HamamsyDepartment of Cardiovascular Surgery Icahn School of Medicine at Mount Sinai New York NY.
Shinichi FukuharaDepartment of Cardiac Surgery University of Michigan Ann Arbor MI.ORCID 0000-0002-7898-5159
Icahn School of Medicine at Mount Sinai · USAlbert Einstein College of Medicine · USHospital of the University of Pennsylvania · USShizuoka Medical Center · JPSt. Luke's University Health Network · USUniversity of Michigan · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The Ross operation appears to restore normal survival in young and middle-aged adults with aortic valve disease. However, there are limited data comparing it with conventional aortic valve replacement. Herein, we compared outcomes of the Ross procedure with mechanical and bioprosthetic aortic valve replacement (M-AVR and B-AVR, respectively). Methods and Results MEDLINE and EMBASE were searched through March 2022 to identify randomized controlled trials and propensity score-matched studies that investigated outcomes of patients aged ≥16 years undergoing the Ross procedure, M-AVR, or B-AVR. The systematic literature search identified 2 randomized controlled trials and 8 propensity score-matched studies involving a total of 4812 patients (Ross: n=1991; M-AVR: n=2019; and B-AVR: n=802). All-cause mortality was significantly lower in the Ross procedure group compared with M-AVR (hazard ratio [HR] [95% CI], 0.58 [0.35-0.97];

Indexed as

Aortic Valve InsufficiencyHeart Valve ProsthesisHeart Valve Prosthesis ImplantationAdolescentAdultAortic ValveHumansMiddle AgedRetrospective StudiesTreatment OutcomeYoung Adultaortic valve substitutebioprosthetic aortic valve replacementmechanical aortic valve replacementRoss proceduresurgical aortic valve replacement

Identifiers

PMID36565200
PMCPMC9973571
OpenAlexW4313524275

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.