ArticleJournal of Alzheimer's disease : JAD2023
Association of Social Support with Mild Cognitive Impairment and Dementia Among Older Women: The Women's Health Initiative Memory Study.
Article in Journal of Alzheimer's disease : JAD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Predictive factors for dementia among older adults in South Korea: an interpretable machine learning analysis.Alzheimer's research & therapy · 2025Article
- Psychometric Properties of a Neuropsychological Assessment Scale for Diagnosing Alzheimer's Disease in the Illiterate and Low-Educated Subjects in Iran.Iranian journal of psychiatry · 2025Article
- Article
- Social support and cognitive activity and their associations with incident cognitive impairment in cognitively normal older adults.BMC geriatrics · 2024Article
- Sources of perceived social support and cognitive function among older adults: a longitudinal study in rural China.Frontiers in aging neuroscience · 2024Article
- Relationship between Social Support, Sarcopenia, and Cognitive Impairment in Chinese Community-Dwelling Older Adults.The journal of nutrition, health & aging · 2023Article
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Authors and funding
12 authors.
Funding
Abstract
backgroundSocial support may be a modifiable risk factor for cognitive impairment. However, few long-term, large prospective studies have examined associations of various forms of social support with incident mild cognitive impairment (MCI) and dementia.
objectiveTo examine associations of perceived social support with incident MCI and dementia among community-dwelling older women.
methodsThis prospective cohort study included 6,670 women from the Women's Health Initiative Memory Study who were cognitively unimpaired at enrollment. We used Cox proportional hazards models to assess associations between perceived social support with incident MCI, dementia, or either MCI/dementia during an average 10.7 (SD = 6.1)-year follow-up. Modelling was repeated for emotional/information support, affection support, tangible support, and positive social interaction subscales of social support.
resultsAmong 6,670 women (average age = 70 years [SD = 3.8]; 97.0% non-Hispanic/Latina; 89.8% White), greater perceived social support was associated with lower risk of MCI/dementia after adjustment for age, ethnicity, race, hormone therapy, education, income, diabetes, hypertension, and body mass index (Tertile [T]3 versus T1: HR = 0.85, 95% CI 0.74-0.99; ptrend = 0.08). Associations were significant for emotional/information support (T3 versus T1: HR = 0.84, 95% CI 0.72-0.97; ptrend = 0.04) and positive social interaction (T3 versus T1: HR = 0.85, 95% CI 0.73-0.99; ptrend = 0.06) subscales. Associations were attenuated and not significant after adjustment for depressive symptom severity.
objectivePerceived social support, emotional/information support, and positive social interaction were associated with incident MCI/dementia among older women. Results were not significant after adjustment for depressive symptom severity. Improving social support may reduce risk of MCI and dementia in older women.
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