Evidence map›Paper›PMID 36564939›Full record

ArticleMilitary medicine2023

Beliefs and Perceived Barriers Regarding Psychedelic-assisted Therapy in a Pilot Study of Service Members and Veterans With a History of Traumatic Brain Injury.

Joshua C Gray, Mikela Murphy, Sierra E Carter, Matthew W Johnson, Aaron S Wolfgang, Michael J Roy, Jessica L Maples-Keller

Open access · hybridAbstract read
In one paragraph

Article in Military medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Perceptions of psychedelic-assisted therapy among Black Americans.Journal of mood and anxiety disorders · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Joshua C GrayDepartment of Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD 20814, USA.ORCID 0000-0002-5351-561X
Mikela MurphyDepartment of Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD 20814, USA.
Sierra E CarterDepartment of Psychology, Georgia State University, Atlanta, GA 30303, USA.
Matthew W JohnsonDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Aaron S WolfgangU.S. Army Medical Department, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA.
Michael J RoyDepartment of Medicine and Center for Neuroscience and Regenerative Medicine, Uniformed Services University, Bethesda, MD 20814, USA.
Jessica L Maples-KellerDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30329, USA.ORCID 0000-0003-4768-7332
Uniformed Services University of the Health Sciences · USBrooke Army Medical Center · USEmory University · USGeorgia State University · USJohns Hopkins University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Neuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Vasiliki Michopoulos · 2018 to 2026
$12.2M
Emory University BIRCWH ProgramK12HD085850 · NICHD · EMORY UNIVERSITY · PI OFOTOKUN, IGHOVWERHA, STERK, CLAIRE E · 2015 to 2023
$4.4M
Emory University BIRCWH ProgramK12AR084234 · NIAMS · EMORY UNIVERSITY · PI Vasiliki Michopoulos, CLAIRE E STERK · 2024 to 2026
$2.6M
NCATS NIH HHS UL1 TR002378NIAMS NIH HHS K12 AR084234NIA NIH HHS U54 AG062334NICHD NIH HHS K12 HD085850
6 · The paper itself

Abstract

introductionPosttraumatic stress disorder (PTSD) and depression are common in service members and veterans, and the response to currently available treatments is often modest at best. Recent studies suggest potential benefit with psychedelic-assisted therapies (PATs), particularly 3,4-methylenedioxymethamphetamine-assisted therapy for PTSD and psilocybin-assisted therapy for depression. This study examined beliefs and perceived barriers regarding PAT among service members and veterans to inform the delivery of these treatments if they are approved by the FDA. MATERIALS AND

methodsTwenty-one service members and veterans (67% male, 81% White, and 43% active duty) with a history of traumatic brain injury and co-occurring cognitive and psychological symptoms completed a measure assessing baseline knowledge and views of PAT, read a brief psychoeducation regarding PAT, and then responded to questions related to their beliefs and perceived barriers to PAT.

resultsBefore psychoeducation, participants reported a neutral view of psychedelic drugs (M = 2.76; range: 1-5), PAT (M = 3.33), and interest in PAT (M = 3.10). After psychoeducation, participants reported a significantly more positive view of psychedelic drugs (M = 3.24, P = .014) and interest in PAT (M = 3.67, P = .016). Overall, participants indicated that they would support PAT availability in medical settings if proven beneficial (M = 4.52; 5 = "agree strongly") and they would support a loved one engaging in PAT (M = 4.29). The most frequently reported health concerns were concern of long-term effects (43%), fear of losing their mind (33%), fear of personality changes (33%), and fear of traumatic brain injury complications (24%). The most frequently endorsed barriers were time commitment, transportation, financial concerns, work, and childcare (33%-19%), with 48% reporting no barriers.

conclusionsThis is the first study to explore beliefs and perceived barriers regarding PAT among service members and veterans. These results indicate that military populations may be interested in PAT, particularly if psychoeducation and outreach regarding these treatments occurred. If FDA approved, it will be important to facilitate command support and address logistical barriers to ensure appropriate access within military contexts.

Indexed as

Brain Injuries, TraumaticHallucinogensMilitary PersonnelStress Disorders, Post-TraumaticVeteransFemaleHumansMalePilot ProjectsHallucinogens

Identifiers

PMID36564939
PMCPMC10629986
OpenAlexW4312129485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.