Evidence map›Paper›PMID 36564827›Full record

ArticleHealth and quality of life outcomes2022

Symptom clusters and impact on quality of life in esophageal cancer patients.

Yanli Wang, Zhongfei Xie, Yuxia Liu, Jianing Wang, Zhijun Liu, Sihan Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health and quality of life outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. The effects of a 3-month walking and dietary education program on the quality of life of patients with esophageal cancer: a 1-year follow-up randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  9. "When symptoms interact and change": longitudinal network analysis of dynamic symptom changes in oral cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  14. Symptom clusters and core symptoms in early postoperative esophageal cancer patients.Frontiers in gastroenterology (Lausanne, Switzerland) · 2026
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Yanli WangDepartment of Radiation Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Zhongfei XieDepartment of Radiation Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Yuxia LiuDepartment of Radiation Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Jianing WangDepartment of Radiation Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Zhijun LiuDepartment of Radiation Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Sihan LiDepartment of Radiation Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China. lisihan303@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophageal cancer patients can experience co-occurring, related symptoms labeled symptom clusters. This study aimed to identify symptom clusters and explore which SCs independently affect the quality of life (QoL) among esophageal cancer patients.

methodsThis cross-sectional study was performed in Shenyang, China, from February 2021 to February 2022. Finally, 118 esophageal cancer patients effectively completed the survey. Questionnaires' information included the Functional Assessment of Cancer Therapy-General (FACT-G), the MD Anderson Symptom Inventory Gastrointestinal Cancer Module (MDASI-GI), the Multidimensions Scale of Perceived Social Support, and demographic and clinical characteristics. Exploratory factor analysis with principal axis factoring was used to identify symptom clusters, and multiple regression analysis was employed to analyze the influencing factors of QoL.

resultsThe mean score of FACT-G was 69.88 (SD = 17.85) among 118 esophageal cancer patients. Four symptom clusters were identified: psychological-somatic, dysphagia, fatigue-pain, and gastrointestinal symptom clusters. Results of regression analysis indicated a significant impact on QoL for chemotherapy (β = 0.140, P < 0.045), psychological-somatic symptom cluster (β = - 0.329, P = 0.013), and social support (β = 0.409, P < 0.001) after adjusting demographic and clinical characteristics. The linear combination explained 47.8% of the variance in QoL.

conclusionsThere is a critical need to emphasize the importance of psychological-somatic symptoms clusters management programs and increasing social support to improve QoL in esophageal cancer patients.

Indexed as

Esophageal NeoplasmsQuality of LifeCross-Sectional StudiesHumansMultivariate AnalysisSyndromeEsophageal cancerQuality of lifeSocial supportSymptoms clusters

Identifiers

PMID36564827
PMCPMC9783739

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.