Evidence map›Paper›PMID 36564795›Full record

ArticlePilot and feasibility studies2022

Protocol for the pilot quasi-experimental controlled trial of a gender-responsive implementation strategy with providers to improve HIV outcomes in Uganda.

K M Sileo, R K Wanyenze, A Anecho, R Luttinen, C Semei, B Mukasa, W Musoke, S H Vermund, S L Dworkin, J F Dovidio and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pilot and feasibility studies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05178979 (A Gender Transformative Implementation Strategy With Providers to Improve HIV), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05178979 nacompletednot on this map

A Gender Transformative Implementation Strategy With Providers to Improve HIV

TypeinterventionalSponsorThe University of Texas at San AntonioRan2021 to 2024Enrolled382ConditionsHIVArmsTraining for HIV care providers (effect on provider outcomes)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

K M SileoDepartment of Public Health, The University of Texas at San Antonio, San Antonio, TX, USA. katelyn.sileo@utsa.edu.ORCID http://orcid.org/0000-0003-3714-2945
R K WanyenzeDepartment of Disease Control and Environmental Health, Makerere University School of Public Health, Kampala, Uganda.
A AnechoDepartment of Disease Control and Environmental Health, Makerere University School of Public Health, Kampala, Uganda.
R LuttinenDepartment of Demography, The University of Texas at San Antonio, San Antonio, TX, USA.
C SemeiMildmay Uganda, Kampala, Uganda.
B MukasaMildmay Uganda, Kampala, Uganda.
W MusokeMildmay Uganda, Kampala, Uganda.
S H VermundYale School of Public Health, New Haven, CT, USA.
S L DworkinSchool of Nursing and Health Studies, University of Washington Bothell, Bothell, WA, USA.
J F DovidioDepartment of Psychology, Yale University, New Haven, CT, USA.
B S TaylorDivision of Infectious Diseases, Department of Medicine, Joe R. & Teresa Lozano Long School of Medicine, UT Health San Antonio, San Antonio, TX, USA.
T S KershawDepartment of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT, USA.
Mildmay Uganda · UGYale University · USMakerere University · UGThe University of Texas at San Antonio · USThe University of Texas Health Science Center at Houston · USThe University of Texas Health Science Center at San Antonio · USUniversity of Washington Bothell · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
A Gender Transformative Implementation Strategy with Providers to Improve HIV Outcomes in UgandaK01MH121663 · NIMH · UNIVERSITY OF TEXAS SAN ANTONIO · PI SILEO, KATELYN MARY · 2020 to 2023
$596k
NCATS NIH HHS UL1 TR001863NIMH NIH HHS K01 MH121663
6 · The paper itself

Abstract

backgroundAntiretroviral treatment (ART) is the most effective clinical intervention for reducing morbidity and mortality among persons living with HIV. However, in Uganda, there are disparities between men and women in viral load suppression and related HIV care engagement outcomes, which suggests problems with the implementation of ART. Gender norms are a known driver of HIV disparities in sub-Saharan Africa, and patient-provider relationships are a key factor in HIV care engagement; therefore, the role of gender norms is important to consider in interventions to achieve the equitable provision of treatment and the quality of ART counseling.

methodsThe overall research objective of this study is to pilot test an implementation strategy (i.e., methods to improve the implementation of an evidence-based intervention) to increase providers' capacity to provide gender-responsive treatment and counseling to men and women on HIV treatment in Uganda. Delivered to HIV providers, this group training adapts evidence-based strategies to reduce gender biases and increase skills to deliver gender-specific and transformative HIV counseling to patients. The implementation strategy will be piloted through a quasi-experimental controlled trial. Clinics will be randomly assigned to either the intervention or control conditions. The trial will assess feasibility and acceptability and explore barriers and facilitators to implementation and future adoption while gathering preliminary evidence on the implementation strategy's effectiveness by comparing changes in patient (N = 240) and provider (N = 80-140) outcomes across intervention and control clinics through 12-month follow-up. Quantitative data will be descriptively analyzed, qualitative data will be analyzed through thematic analysis, and these data will be mixed during the presentation and interpretation of results where appropriate. DISCUSSION: This pilot intervention trial will gather preliminary evidence on the acceptability, feasibility, and potential effect of a novel implementation strategy to improve men and women's HIV care engagement, with the potential to reduce gender disparities in HIV outcomes.

trial registrationClinicaltrials.gov NCT05178979 , retrospectively registered on January 5, 2022.

Indexed as

HIV/AIDSImplementation scienceInterventionUganda

Identifiers

PMID36564795
PMCPMC9783690
OpenAlexW4312117634

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.