ArticleBMC public health2022
Associations of environmental factors with total cholesterol level of middle-aged and elderly people in China.
Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 16 citations in OpenAlex.
- Association of serum essential and non-essential elements with dyslipidemia in patients with cardiovascular disease in Western Iran: an application of Bayesian kernel machine regression.BMC cardiovascular disorders · 2026Article
- Spatio-temporal distribution of influencing factors of cardiovascular disease in the United States.Frontiers in public health · 2025Article
- Study on the mechanism of vitamin E alleviating non-alcoholic fatty liver function based on non-targeted metabolomics analysis in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
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- When "Aging" meets "Intelligence": smart health cognition and intentions of older adults in rural Western China.Frontiers in psychiatry · 2024Article
- Influence of Air Pollution Exposures on Cardiometabolic Risk Factors: a Review.Current environmental health reports · 2023Review
- Spatial distribution of anti-mullerian hormone in females of childbearing age in China under the influence of geographical environmental factors.BMC public health · 2023Article
- Exploring observed and instructed mHealth use in the middle-aged and elderly people (MAEP): A social learning perspective.Digital healthArticle
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDyslipidemia is a key factor causing cardio cerebrovascular diseases, and the total cholesterol (TC) is an important lipid indicator among them. Studies have shown that environmental factors have a strong association with TC levels. Previous studies only focused on the seasonal variation of TC level and the short-term effects of some environmental factors on TC level over time, and few studies explored the geographical distribution of TC level and quantified the impact of environmental factors in space.
methodsBased on blood test data which was from China Health and Retirement Longitudinal Study (Charls) database, this study selected the TC level test data of middle-aged and elderly people in China in 2011 and 2015, and collected data from 665 meteorological stations and 1496 air pollutant monitoring stations in China. After pretreatment, the spatial distribution map of TC level was prepared and the regional statistics were made. GeoDetector and geographically weighted regression (GWR) were used to measure the relationship between environmental factors and TC level.
resultsThe TC level of middle-aged and elderly in China was higher in females than in males, and higher in urban areas than in rural areas, showing a clustered distribution. The high values were mainly in South China, Southwest China and North China. Temperature, humidity, PM
conclusionsThere were gender and urban-rural differences in TC levels among the middle-aged and elderly population in China, showing aggregation in geographical distribution. Meteorological factors and air pollutants may be very important control factors, and their influencing mechanism needs further study.
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