Evidence map›Paper›PMID 36564727›Full record

ArticleBMC pediatrics2022

Antibiotic-impregnated calcium sulfate for the treatment of pediatric hematogenous osteomyelitis.

Rui Tao, Jian-Qun Wu, Ji-Wei Luo, Liang Hong, Chun-Hao Zhou, Guo-Yun Cheng, Cheng-He Qin

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rui TaoDepartment of Orthopaedics, Southern Medical University Zengcheng Branch of Nanfang Hospital, No. 28 Chuangxin Avenue Yongning Street, Zengcheng District, Guangzhou, 511340, People's Republic of China.
Jian-Qun WuDepartment of Bone and Joint, School ofMedicine, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, 518055, People's Republic of China.
Ji-Wei LuoDepartment of Orthopaedics and Traumatology, Southern Medical University Nanfang Hospital, No. 1838, Guangzhou Ave. North, Guangzhou, Guangdong, 510515, People's Republic of China.
Liang HongDepartment of Orthopaedics, Southern Medical University Zengcheng Branch of Nanfang Hospital, No. 28 Chuangxin Avenue Yongning Street, Zengcheng District, Guangzhou, 511340, People's Republic of China.
Chun-Hao ZhouDepartment of Orthopaedics and Traumatology, Southern Medical University Nanfang Hospital, No. 1838, Guangzhou Ave. North, Guangzhou, Guangdong, 510515, People's Republic of China.
Guo-Yun ChengDepartment of Orthopaedics and Traumatology, Second Clinical Medical School, Guangdong Second Provincial General Hospital, Southern Medical University, Guangzhou, 510317, People's Republic of China.
Cheng-He QinDepartment of Orthopaedics and Traumatology, Southern Medical University Nanfang Hospital, No. 1838, Guangzhou Ave. North, Guangzhou, Guangdong, 510515, People's Republic of China. orthoqin@163.com.
Nanfang Hospital · CNSouthern Medical University · CNSouthern University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntibiotic-impregnated calcium sulfate has excellent curative efficacy in chronic osteomyelitis. However, its curative efficacy in pediatric hematogenous osteomyelitis has not been sufficiently studied. The purpose of this study was to evaluate the curative effects of antibiotic-impregnated calcium sulfate in the treatment of pediatric hematogenous osteomyelitis.

methodsOverall, twenty-one pediatric patients with hematogenous osteomyelitis treated at our hospital between 2013 and 2018 were included for assessment. The clinical history, clinical manifestation, infection recurrence rate, sinus leakage, incision leakage, pathological fractures, bone growth and surgical procedures were analyzed.

resultsThe infection recurrence rate was 0% (0/21) at a minimum of 31 months (range 31 to 91 months) of follow-up. Postoperative incision leakage was found in one pediatric patient. Osteolysis was found in one pediatric patient. Acceleration of bone growth occurred in one pediatric patient. Retardation of bone growth occurred in one pediatric patient. Genu valgus deformity occurred in one pediatric patient.

conclusionsAlthough noninfectious complications occurred, the curative effect of antibiotic-impregnated calcium sulfate in pediatric hematogenous osteomyelitis was satisfactory.

Indexed as

Anti-Bacterial AgentsOsteomyelitisCalcium SulfateChildDebridementHumansTreatment OutcomeAnti-Bacterial AgentsCalcium SulfateCalcium sulfateHematogenous osteomyelitisLocal antibioticPediatric

Identifiers

PMID36564727
PMCPMC9783740
OpenAlexW4312179170

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.