ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Censoring in the time trade-off valuation of worse-than-dead EQ-5D-5L health states: can a time-based willingness-to-accept question be the solution?
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Making Composite Time Trade-Off Sensitive for Worse-than-Dead Health States.PharmacoEconomics · 2025Trial
- Valuation of EQ-5D-5L health states from cancer patients' perspective: a feasibility study.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- Beyond 10-year lead-times in EQ-5D-5L: leveraging alternative lead-times in willingness-to-accept questions to capture preferences for worse-than-dead states and their implication.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- Health-related quality of life and associated factors in elderly individuals with dyslipidemia in rural Northern China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Quantifying health-related quality of life in Malaysian type 2 diabetes: focusing on complication types and severity.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
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Authors and funding
6 authors.
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Abstract
purposeThe left censoring of values at -1 by design of the composite time trade-off (cTTO) tasks leads to excessive amount of -1 values in some EQ-5D-5L valuation studies. This study aimed to investigate whether a time-based willingness-to-accept (tWTA) question can be used to elicit values lower than -1 and improve the estimation of EQ-5D-5L values.
methodsAt the end of each cTTO task in the Taiwanese EQ-5D-5L valuation study, if the value of the health state was indicated to be lower than -1, a tWTA question eliciting the indifference point between a hypothetical life (i.e. x number of years in full health followed by 10 years in the health state) and immediate death was used to estimate its uncensored value. We compared the statistical characteristics of the censored and uncensored data.
resultsFour hundred and twenty-nine of 1,000 respondents were offered the tWTA question in a total of 1,071 cTTO tasks. In 79.55% of those tasks, indifference was not reached. Spearman's correlation with level summary score was -0.41 and -0.40 for negative uncensored and censored data, respectively. The logical inconsistency rates of the uncensored and censored data were 0.88% vs. 0.29%, respectively. Modelling of the uncensored data resulted in coefficients with greater uncertainty and much lower predictions.
conclusionsThe elicitation of values lower than -1 using a tWTA question that grants more time for trading seems not a promising solution to the value censoring of the cTTO tasks. Other strategies for valuation of very poor health states should be explored.
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