Evidence map›Paper›PMID 36564332›Full record

ArticleHematology, transfusion and cell therapy

Clinical outcome and prognosis of patients with acute myeloid leukemia submitted to chemotherapy with 5 years of follow-up.

Kaira Mara Cordeiro de Albuquerque, Caroline Brandão Joventino, Lia Correia Moreira, Hermano Alexandre Lima Rocha, Lívia Andrade Gurgel, Deivide de Sousa Oliveira, Carlos Ewerton Maia Rodrigues

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Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Diagnostic and prognostic relevance ofLeukemia research reports · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaira Mara Cordeiro de AlbuquerqueUniversidade de Fortaleza (Unifor), Fortaleza, CE, Brazil; Fortaleza General Hospital (HGF), Fortaleza, CE, Brazil. Electronic address: drakairahematologista@gmail.com.
Caroline Brandão JoventinoUniversidade de Fortaleza (Unifor), Fortaleza, CE, Brazil.
Lia Correia MoreiraUniversidade de Fortaleza (Unifor), Fortaleza, CE, Brazil.
Hermano Alexandre Lima RochaUniversidade Federal do Ceará (UFC), Fortaleza, CE, Brazil.
Lívia Andrade GurgelFortaleza General Hospital (HGF), Fortaleza, CE, Brazil; Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil.
Deivide de Sousa OliveiraFortaleza General Hospital (HGF), Fortaleza, CE, Brazil; Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil.
Carlos Ewerton Maia RodriguesUniversidade de Fortaleza (Unifor), Fortaleza, CE, Brazil; Fortaleza General Hospital (HGF), Fortaleza, CE, Brazil; Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to evaluate the clinical-epidemiological profile, associated risk factors and clinical outcomes of patients with acute myeloid leukemia (AML), identifying the main causes of morbidity and mortality and overall survival rate of patients at five years of follow-up.

methodThis was a retrospective cohort study evaluating the prognosis and clinical outcomes of 222 patients diagnosed with AML at three large hematology centers in Ceará (northeastern Brazil) over a period of five years.

resultsThe mean age at diagnosis was 44.1 ± 16 years, with a female prevalence of 1.3:1. No additional relevant risk factors associated with the development of AML were found, except for the well-established cytogenetic assessment. The overall 5-year survival rate was 39.4% (95%CI: 35.47 - 42.17). The main causes of death were disease progression (37.72%; n = 84) and sepsis (31.58%; n = 70).

conclusionThe clinical outcomes in our sample of AML patients were similar to those of other reported groups. Disease progression and infection were the main causes of death. Access to diagnostic flow cytometry and karyotyping was greater in our sample than in the national average. As expected, overall survival differed significantly according to the risk, as determined by cytogenetic testing.

Indexed as

Acute myeloid leukemiaClinical outcomeLeukemiaOverall survivalPrognosis

Identifiers

PMID36564332
PMCPMC10935468

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.