ArticleJournal of neurointerventional surgery2023
Updated estimates of large and medium vessel strokes, mechanical thrombectomy trends, and future projections indicate a relative flattening of the growth curve but highlight opportunities for expanding endovascular stroke care.
Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Impact of Artificial Intelligence-Based Triage on Stroke Workflow Metrics: A Systematic Review and Meta-Analysis.Cardiovascular and interventional radiology · 2026Pooled it
- Imaging-to-recanalization delay influences perfusion CT threshold calibration for follow-up infarct volume estimation.European journal of radiology open · 2026Article
- Intravenous Thrombolysis in Distal Medium Middle Cerebral Artery Occlusion Patients with Unsuccessful Mechanical Reperfusion.Clinical neuroradiology · 2026Article
- RAPID-LC: rapid evidence-to-practice uptake of large core thrombectomy across a stroke consortium.Journal of neurology · 2026Article
- Management of intracranial arterial stenosis during mechanical thrombectomy: Survey of neuro-interventionalists.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Feasibility of a Multi-Laboratory Model of Middle Cerebral Artery Thromboembolic Stroke with Thrombolysis: TE-MCAo.Translational stroke research · 2026Article
- Rising tide of middle meningeal artery embolization for chronic subdural hematomas: current volumes and future growth compared with cerebral aneurysm and stroke interventions.Journal of neurointerventional surgery · 2026Article
- Extensive ischemic change on stroke presentation is uncommon: A population-based study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025Article
- The implementation of an artificial intelligence-based software for large vessel occlusion stroke improves door-to-puncture time at a comprehensive stroke center.Internal and emergency medicine · 2025Article
- Effect of Time from Puncture to Recanalization on Poststroke Disposition and Associated Costs.Stroke (Hoboken, N.J.) · 2025Article
- Automated collateral assessment restricted to the hypoperfused area for distal vessel occlusions in ischemic stroke.European radiology · 2025Article
- The risk of endovascular thrombectomy in acute ischemic stroke patients with large vessel occlusions harboring unruptured intracranial aneurysms.BMC neurology · 2025Article
- Microguidewire stiffness for microcatheter and aspiration catheter navigation in tortuous vessels.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Does endovascular thrombectomy using super-bore 0.088" large distal platform offer advantages over balloon guide catheters in acute ischemic stroke secondary to large vessel occlusion?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Early detection of contrast-induced encephalopathy after mechanical thrombectomy using flat-detector CT: incidence, risk factors, and clinical implications.Neuroradiology · 2025Article
- Population-based estimates suggest middle meningeal artery embolization for subdural hematomas could significantly expand the scope of neurovascular therapies.Journal of neurointerventional surgery · 2025Article
- Trends in Ischemic Stroke Hospitalization and Outcomes in the United States Pre- and Peri-COVID-19 Pandemic: A National Inpatient Sample Study.Journal of clinical medicine · 2025Article
- Vascular injury and occurrence of microthrombi after endovascular therapy for acute ischaemic stroke in a thromboembolic model.BMJ neurology open · 2025Article
- Prevalence of large vessel occlusions in an unselected hospital-based stroke cohort in Sweden.Frontiers in neurology · 2025Article
- Associations of arterial oxygen partial pressure with all‑cause mortality in critically ill ischemic stroke patients: a retrospective cohort study from MIMIC IV 2.2.BMC anesthesiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA study was undertaken to determine the incidence of acute ischemic stroke (AIS) and strokes related to large (LVO) and medium (MVO) vessel occlusions, and to estimate annual mechanical thrombectomy (MT) volume, past trends and future growth.
methodsA population-based analysis was performed to estimate the rate of AIS, LVOs (internal carotid artery terminus, M1 branch of the middle cerebral artery, basilar artery) and MVOs (M2 and M3 branches of the middle cerebral artery, anterior and posterior cerebral arteries). MT estimates were determined from multiple governmental data sources. Annual US numbers were adjusted for population growth.
resultsThe incidence of AIS is estimated at 216 (95% CI 199 to 238)/100 000 persons/year or 718 191 (95% CI 661 483 to 791 121) AIS/year in the USA. A vascular occlusion was observed in 21% of patients with AIS (95% CI 15 to 29). The rate of LVO was 24/100 000 persons/year (95% CI 19 to 31) or 80 075 (95% CI 62 457 to 104 375) LVOs/year, and the rate of MVO was 20/100 000 persons/year or 65 798 (95% CI 45 555 to 95 110) MVOs/year. MT estimates for 2021 are 39 164 procedures with a flattening of the growth curve from 2019 (9%, 2020-2021; 4%, 2019-2020) as opposed to initial steep growth from 2015 to 2018. Current MT procedures represent 5% of all AIS, 27% of all vascular occlusions (LVO+MVO) and 38% of all LVO and M2 occlusions. The current trajectory indicates a future growth of 5-10%/year for the next several years.
conclusionA decline in MT growth is observed. The incidence of LVO+MVO is estimated at 44/100 000 persons/year or almost 144 000 large and medium vessel strokes annually. Of these, currently an estimated 27% undergo an MT procedure, indicating an opportunity for growth. Further expansion may require focusing on the elderly, medium vessel strokes and workflow efficiencies from diagnosis to treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.