Evidence map›Paper›PMID 36564185›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Specific Inhibition of Interpeduncular Nucleus GABAergic Neurons Alleviates Anxiety-Like Behaviors in Male Mice after Prolonged Abstinence from Methamphetamine.

Xing Xu, Nanqin Li, Jun Wen, Ping Yang, Xue Lu, Zilin Wang, Teng He, Yu Fan, Bo Xu, Feifei Ge and 1 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Specific Glutamatergic Projection to Claustrum for Regulating Methamphetamine Abstinence Anxiety-Like Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Distinct eLPBTheranostics · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xing XuDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Nanqin LiDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Jun WenDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Ping YangDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Xue LuDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Zilin WangDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Teng HeDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Yu FanDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China.ORCID 0000-0001-6813-6797
Bo XuDepartment of Anesthesiology, General Hospital of Southern Theatre Command of the People's Liberation Army, Guangzhou 510010, China.
Feifei GeDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China guanxw918@njucm.edu.cn ffge@njucm.edu.cn.ORCID 0000-0003-1336-8587
Xiaowei GuanDepartment of Human Anatomy and Histoembryology, Nanjing University of Chinese Medicine, Nanjing 210023, China guanxw918@njucm.edu.cn ffge@njucm.edu.cn.
Nanjing University of Chinese Medicine · CNGeneral Hospital of Guangzhou Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety is one of the most common withdrawal symptoms of methamphetamine (METH) abuse, which further drives relapse to drugs. Interpeduncular nucleus (IPN) has been implicated in anxiety-like behaviors and addiction, yet its role in METH-abstinence-induced anxiety remains unknown. Here, we found that prolonged abstinence from METH enhanced anxiety-like behaviors in male mice, accompanied by more excited IPN GABAergic neurons, as indicated by the increased c-

Indexed as

Amphetamine-Related DisordersInterpeduncular NucleusMethamphetamineSubstance Withdrawal SyndromeAnimalsAnxietyGABAergic NeuronsMaleMiceMethamphetamineanxietydrug abuseGABAergic neuronsinterpeduncular nucleusmethamphetaminewithdrawal symptoms

Identifiers

PMID36564185
PMCPMC9899084
OpenAlexW4312129424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.