Evidence map›Paper›PMID 36564013›Full record

ReviewFEMS microbiology reviews2023

Illuminating the oral microbiome and its host interactions: tools and approaches for molecular ecological studies.

Jens Kreth, Justin Merritt

Open access · bronzeAbstract readReview
In one paragraph

Review in FEMS microbiology reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jens KrethDepartment of Restorative Dentistry, School of Dentistry, Oregon Health and Science University, MRB433, 3181 SW Sam Jackson Park Rd., #L595, Portland, OR 97239, United States.ORCID 0000-0002-8599-8310
Justin MerrittDepartment of Restorative Dentistry, School of Dentistry, Oregon Health and Science University, MRB433, 3181 SW Sam Jackson Park Rd., #L595, Portland, OR 97239, United States.ORCID 0000-0002-3464-0490
Oregon Health & Science University · US

Funding

Advancing studies of polymicrobial diseases via streptococcal geneticsR35DE028252 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI MERRITT, JUSTIN · 2018 to 2025
$7.8M
Pyruvate oxidase: a molecular determinant of commensalism among the oral microbiomeR01DE029492 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRETH, JENS · 2020 to 2024
$2.5M
The LytTR Regulatory Systems of Streptococcus mutansR01DE022083 · NIDCR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI MERRITT, JUSTIN · 2013 to 2016
$1.5M
Streptococcal secretion of pyruvate - a novel antioxidant strategy in the oral biofilmR21DE029612 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRETH, JENS · 2020 to 2021
$424k
NIDCR NIH HHS R01 DE022083NIDCR NIH HHS R01 DE029492NIDCR NIH HHS R21 DE029612NIDCR NIH HHS R35 DE028252
6 · The paper itself

Abstract

A more comprehensive understanding of oral diseases like caries and periodontitis is dependent on an intimate understanding of the microbial ecological processes that are responsible for disease development. With this review, we provide a comprehensive overview of relevant molecular ecology techniques that have played critical roles in the current understanding of human oral biofilm development, interspecies interactions, and microbiome biogeography. The primary focus is on relevant technologies and examples available in the oral microbiology literature. However, most, if not all, of the described technologies should be readily adaptable for studies of microbiomes from other mucosal sites in the body. Therefore, this review is intended to serve as a reference guide used by microbiome researchers as they inevitably transition into molecular mechanistic studies of the many significant phenotypes observed clinically.

Indexed as

MicrobiotaBiofilmsHumansmicrobial ecologymicrobial geneticsmicrobiomeoral biofilm

Identifiers

PMID36564013
PMCPMC9936263
OpenAlexW4312128810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.