Evidence map›Paper›PMID 36563301›Full record

ArticleHead & neck2023

Intrathyroidal parathyroid adenomas: Scoping review on clinical presentation, preoperative localization, and surgical treatment.

Shravan V Gowrishankar, Rohan Bidaye, Tilak Das, Veronika Majcher, Brian Fish, Ruth Casey, Liam Masterson

Abstract readScoping Review
In one paragraph

Article in Head & neck, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  6. Indocyanine green fluorescence in parathyroidectomy: enhancing efficiency through real-time adenoma identification.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shravan V GowrishankarSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0552-6314
Rohan BidayeDepartment of Otolaryngology-Head & Neck Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID 0000-0002-6735-8037
Tilak DasDepartment of Neuroradiology and Head & Neck Imaging, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Veronika MajcherDepartment of Neuroradiology and Head & Neck Imaging, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Brian FishDepartment of Otolaryngology-Head & Neck Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Ruth CaseyDepartment of Endocrinology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID 0000-0003-4058-3135
Liam MastersonDepartment of Otolaryngology-Head & Neck Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID 0000-0001-7214-030X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrathyroidal parathyroid adenomas (IPAs) are a rare cause of primary hyperparathyroidism. They are often difficult to localize preoperatively and intraoperatively, making diagnosis and treatment challenging. Current data on IPAs are sparse and fragmented in the literature. This makes it difficult to compare the effectiveness of different imaging and surgical techniques. To address this issue, this scoping review maps the literature on IPAs, focusing on four domains: clinical presentation, current localization methods, different surgical techniques, and histopathological features. A search of MEDLINE, Embase, and the Cochrane Library was conducted, with 19 studies meeting the inclusion criteria. The characteristics of IPAs on ultrasound, fine-needle aspiration, CT, MRI, sestamibi-based techniques, and selective venous sampling are summarized. Emerging imaging modalities, including autofluorescence, are introduced. Surgical methods and intraoperative factors that correlate with high success rates for removal are highlighted. This review also identifies gaps in knowledge to guide further research into this area.

Indexed as

AdenomaParathyroid NeoplasmsDiagnostic ImagingHumansParathyroid GlandsRadiopharmaceuticalsTechnetium Tc 99m SestamibiUltrasonographyRadiopharmaceuticalsTechnetium Tc 99m Sestamibiimaging techniquesintrathyroid parathyroid adenomalobectomythyroid and parathyroid surgeryultrasound

Identifiers

PMID36563301
PMCPMC10108101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.