Evidence map›Paper›PMID 36563291›Full record

ArticleJournal of medicinal chemistry2023

Structural Determinants of Indole-2-carboxamides: Identification of Lead Acetamides with Pan Antimycobacterial Activity.

Pankaj Bhattarai, Pooja Hegde, Wei Li, Pavan Kumar Prathipati, Casey M Stevens, Lixinhao Yang, Hinman Zhou, Amit Pandya, Katie Cunningham, Jenny Grissom and 9 more

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Bisindole Compounds-Synthesis and Medicinal Properties.Antibiotics (Basel, Switzerland) · 2024
    Review
  6. Review
  7. New therapeutic strategies forExpert review of anti-infective therapy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Pankaj BhattaraiDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Pooja HegdeDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Wei LiMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado80523, United States.
Pavan Kumar PrathipatiDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Casey M StevensDepartment of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma73019, United States.
Lixinhao YangSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia30332, United States.
Hinman ZhouDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Amit PandyaDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Katie CunninghamDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Jenny GrissomDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Mariaelena Roman SoteloDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Melanie SowardsDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Lilian CalistoDepartment of Oral Biology, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Christopher J DestacheDepartment of Pharmacy Practice, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
Sonia Rocha-SanchezDepartment of Oral Biology, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.
James C GumbartSchool of Physics and School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia30332, United States.ORCID 0000-0002-1510-7842
Helen I ZgurskayaDepartment of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma73019, United States.ORCID 0000-0001-8929-4727
Mary JacksonMycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado80523, United States.ORCID 0000-0002-9212-0258
E Jeffrey NorthDepartment of Pharmacy Sciences, Creighton University, 2500 California Plaza, Omaha, Nebraska68178, United States.ORCID 0000-0001-7644-030X

Funding

Understanding the progression of hearing loss in an endolymphatic hydrops modelP20GM139762 · NIGMS · CREIGHTON UNIVERSITY · PI Peter Stephen Steyger · 2021 to 2026
$16.1M
MmpL3 as a target for novel anti-TB agentsR01AI116525 · NIAID · COLORADO STATE UNIVERSITY · PI JACKSON, MARY · 2015 to 2024
$5.3M
NIAID NIH HHS R01 AI116525NIGMS NIH HHS P20 GM139762
6 · The paper itself

Abstract

Tuberculosis (TB), caused by

Indexed as

Mycobacterium Infections, NontuberculousMycobacterium tuberculosisTuberculosisAcetamidesAntitubercular AgentsHumansIndolesMicrobial Sensitivity TestsAcetamidesAntitubercular AgentsIndoles

Identifiers

PMID36563291
PMCPMC10010622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.