Evidence map›Paper›PMID 36563134›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Combating Escherichia coli O157:H7 with Functionalized Chickpea-Derived Antimicrobial Peptides.

Qiao He, Zhehao Yang, Zhipeng Zou, Mengyan Qian, Xiaolei Wang, Xinhui Zhang, Zhongping Yin, Jinhai Wang, Xingqian Ye, Donghong Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 43 citations in OpenAlex.

  1. Lauric Acid Microemulsions InhibitFoods (Basel, Switzerland) · 2026
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  3. Overcoming Methicillin-ResistantResearch (Washington, D.C.) · 2026
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  5. Recent Advances in Nanoparticle-Mediated Antibacterial Photodynamic Therapy.International journal of molecular sciences · 2025
    Review
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  7. Article
  8. Article
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  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Qiao HeCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.ORCID 0000-0003-0850-7706
Zhehao YangCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Zhipeng ZouCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Mengyan QianCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Xiaolei WangCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Xinhui ZhangCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Zhongping YinJiangxi Key Laboratory of Natural Products and Functional Foods, Jiangxi Agricultural University, Nanchang, Jiangxi Province, 330045, P. R. China.
Jinhai WangDepartment of Colorectal Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Xingqian YeCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Donghong LiuCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.
Mingming GuoCollege of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P. R. China.ORCID 0000-0001-6546-4461
Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CNJiangxi Agricultural University · CN

Funding

National Natural Science Foundation of China 32001799National Natural Science Foundation of China 32272474Natural Science Foundation of Zhejiang Province, China LQ20C200014Science Fund for Distinguished Young Scholars of Zhejiang Province LR23C200002
6 · The paper itself

Abstract

The rapid dissemination of antibiotic resistance accelerates the desire for new antibacterial agents. Here, a class of antimicrobial peptides (AMPs) is designed by modifying the structural parameters of a natural chickpea-derived AMP-Leg2, termed "functionalized chickpea-derived Leg2 antimicrobial peptides" (FCLAPs). Among the FCLAPs, KTA and KTR show superior antibacterial efficacy against the foodborne pathogen Escherichia coli (E. coli) O157:H7 (with MICs in the range of 2.5-4.7 µmol L

Indexed as

CicerEscherichia coli O157Anti-Bacterial AgentsAntimicrobial PeptidesPeptidesAnti-Bacterial AgentsAntimicrobial PeptidesPeptidesantimicrobial peptidesdual-targeting mechanism of actionEscherichia coli O157:H7foodborne pathogen interventionmembrane-mediated antimicrobial mechanism

Identifiers

PMID36563134
PMCPMC9951321
OpenAlexW4312113232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.