Evidence map›Paper›PMID 36563032›Full record

ArticleJMIR public health and surveillance2022

Drug Abuse Ontology to Harness Web-Based Data for Substance Use Epidemiology Research: Ontology Development Study.

Usha Lokala, Francois Lamy, Raminta Daniulaityte, Manas Gaur, Amelie Gyrard, Krishnaprasad Thirunarayan, Ugur Kursuncu, Amit Sheth

Abstract read
In one paragraph

Article in JMIR public health and surveillance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Usha LokalaAI Institute, University of South Carolina, Columbia, SC, United States.ORCID 0000-0001-6186-2171
Francois LamyDepartment of Society and Health, Mahidol University, Salaya, Thailand.ORCID 0000-0001-6542-1381
Raminta DaniulaityteCollege of Health Solutions, Arizona State Univeristy, Phoenix, AZ, United States.ORCID 0000-0001-6507-3866
Manas GaurAI Institute, University of South Carolina, Columbia, SC, United States.ORCID 0000-0002-5411-2230
Amelie GyrardDepartment of IoT and AI, Trialog Information Technology & Services, Ile-de-France, France.ORCID 0000-0003-3938-5617
Krishnaprasad ThirunarayanDepartment of Computer Science & Engineering, Wright State University, Dayton, OH, United States.ORCID 0000-0002-7041-6963
Ugur KursuncuAI Institute, University of South Carolina, Columbia, SC, United States.ORCID 0000-0002-8108-9590
Amit ShethAI Institute, University of South Carolina, Columbia, SC, United States.ORCID 0000-0002-0021-5293

Funding

Toxoplasma encephalitis in AIDS:Bradyzoite RegulationsR01AI039454 · NIAID · YESHIVA UNIVERSITY · PI WEISS, LOUIS M. · 1996 to 2009
$3.1M
Trending: Social media analysis to monitor cannabis and synthetic cannabinoid useR01DA039454 · NIDA · WRIGHT STATE UNIVERSITY · PI DANIULAITYTE, RAMINTA, SHETH, AMIT P · 2014 to 2016
$1.4M
eDarkTrends: monitoring cryptomarkets to identify emerging trends of illicit synthetic opioids useR21DA044518 · NIDA · WRIGHT STATE UNIVERSITY · PI DANIULAITYTE, RAMINTA, LAMY, FRANCOIS RENE · 2017 to 2018
$408k
A Study of Social Web Data on Buprenorphine Abuse Using Semantic Web TechnologyR21DA030571 · NIDA · WRIGHT STATE UNIVERSITY · PI DANIULAITYTE, RAMINTA, SHETH, AMIT P · 2011 to 2012
$402k
NIAID NIH HHS R01 AI039454NIDA NIH HHS R01 DA039454NIDA NIH HHS R21 DA030571NIDA NIH HHS R21 DA044518
6 · The paper itself

Abstract

backgroundWeb-based resources and social media platforms play an increasingly important role in health-related knowledge and experience sharing. There is a growing interest in the use of these novel data sources for epidemiological surveillance of substance use behaviors and trends.

objectiveThe key aims were to describe the development and application of the drug abuse ontology (DAO) as a framework for analyzing web-based and social media data to inform public health and substance use research in the following areas: determining user knowledge, attitudes, and behaviors related to nonmedical use of buprenorphine and illicitly manufactured opioids through the analysis of web forum data Prescription Drug Abuse Online Surveillance; analyzing patterns and trends of cannabis product use in the context of evolving cannabis legalization policies in the United States through analysis of Twitter and web forum data (eDrugTrends); assessing trends in the availability of novel synthetic opioids through the analysis of cryptomarket data (eDarkTrends); and analyzing COVID-19 pandemic trends in social media data related to 13 states in the United States as per Mental Health America reports.

methodsThe domain and scope of the DAO were defined using competency questions from popular ontology methodology (101 ontology development). The 101 method includes determining the domain and scope of ontology, reusing existing knowledge, enumerating important terms in ontology, defining the classes, their properties and creating instances of the classes. The quality of the ontology was evaluated using a set of tools and best practices recognized by the semantic web community and the artificial intelligence community that engage in natural language processing.

resultsThe current version of the DAO comprises 315 classes, 31 relationships, and 814 instances among the classes. The ontology is flexible and can easily accommodate new concepts. The integration of the ontology with machine learning algorithms dramatically decreased the false alarm rate by adding external knowledge to the machine learning process. The ontology is recurrently updated to capture evolving concepts in different contexts and applied to analyze data related to social media and dark web marketplaces.

conclusionsThe DAO provides a powerful framework and a useful resource that can be expanded and adapted to a wide range of substance use and mental health domains to help advance big data analytics of web-based data for substance use epidemiology research.

Indexed as

COVID-19Social MediaSubstance-Related DisordersAnalgesics, OpioidArtificial IntelligenceHumansPandemicsUnited StatesAnalgesics, Opioidcryptomarketillicit drugsknowledge graphontologysemantic websocial media

Identifiers

PMID36563032
PMCPMC9823583

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.