ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2023
Independent and Joint Associations of Age, Pre-pregnancy BMI, and Gestational Weight Gain with Adverse Pregnancy Outcomes in Gestational Diabetes Mellitus.
Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 12 citations in OpenAlex.
- Independent and synergistic effects of OGTT-based hyperglycemia phenotypes and gestational weight gain on feto-maternal outcomes in GDM.BMC pregnancy and childbirth · 2026Article
- [Impact of pre-pregnancy body mass index on maternal and infant outcomes in twin pregnancies].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Special Issue "Molecular Insight into Gestational Diabetes Mellitus".International journal of molecular sciences · 2026Article
- The correlation between serum magnesium, phosphorus, and calcium levels during pregnancy and the risk of gestational diabetes mellitus as well as adverse pregnancy outcomes.Frontiers in clinical diabetes and healthcare · 2026Article
- Identifying critical windows for macrosomia prevention: a study on the association between phase-specific dynamic BMI changes and macrosomia risk.Frontiers in endocrinology · 2026Article
- Article
- Related differences in fecal bacteria of Chinese northern pregnant women of different ages: associations with maternal clinical indicators and neonatal outcomes.Frontiers in microbiology · 2025Article
- Effect of Goal-Directed Fluid Therapy on Hypotension From Spinal Anesthesia in Older Parturients Having Cesarean Section: A Randomized Controlled Trial.Anesthesiology research and practice · 2025Article
- Secular trend of gestational diabetes mellitus and its interaction effect with advanced maternal age on adverse maternal-perinatal outcomes among primiparous singleton and twin pregnancies in Hubei, China (2011-2019).Frontiers in endocrinology · 2025Article
- D-Chiro Inositol Supplementation and the Occurrence of Gestational Diabetes: A Randomized Controlled Trial in China.Food science & nutrition · 2025Article
- Improved pregnancy outcome in gestational diabetes mellitus patients treated with insulin aspart and metformin: a comparative study.American journal of translational research · 2024Article
- Association between serum free fatty acids and gestational diabetes mellitus.Frontiers in endocrinology · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
introductionTo explore the independent and combined effects of maternal age, pre-pregnancy body mass index (BMI), and gestational weight gain (GWG) on pregnancy outcomes in gestational diabetes mellitus (GDM).
methodsA total of 2171 pregnant women with GDM attending the Women's Hospital of Zhejiang University were retrospectively included. We compared pregnancy outcomes in different age, BMI, and GWG groups after adjusting for confounding variables.
resultsResults showed that (1) advanced maternal age increased the risk of primary Cesarean section and hypertensive disorders of pregnancy (HDP) in normal weight; (2) independent of age and GWG, high BMI significantly increased the risk of HDP, primary Cesarean section, and macrosomia; (3) Women with excessive GWG had a higher risk of primary Cesarean section and HDP, even they were ≤ 29 years old or normal weight, respectively; (4) Pregnant women with inadequate GWG had a higher risk of preterm birth and a lower risk of macrosomia in both the 30-34 age group and the normal weight group; (5) BMI was a better predictor of HDP than GWG among women younger than 30.
conclusionsAmong the GDM population, women over the age of 35, overweight and obese, or with an excessive GWG were more prone to adverse pregnancy outcomes, especially primary Cesarean delivery and HDP.
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