Evidence map›Paper›PMID 36562903›Full record

ArticleInternational urology and nephrology2023

Exercise intolerance and malnutrition associated with all-cause mortality in elderly patients undergoing peritoneal dialysis: a single-center prospective cohort study.

Hiroki Yabe, Keiko Okada, Kenichi Kono, Yuto Imoto, Ayaka Onoyama, Sayaka Ito, Yoshifumi Moriyama, Hirotake Kasuga, Yasuhiko Ito

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In one paragraph

Article in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hiroki YabeDepartment of Physical Therapy, School of Rehabilitation Sciences, Seirei Christopher University, 3453 Mikatahara, Kita-Ku, Hamamatsu, Shizuoka, 433-8558, Japan. hiroki-y@seirei.ac.jp.ORCID http://orcid.org/0000-0002-0444-6830
Keiko OkadaDepartment of Nephrology, Nagoya Kyoritsu Hospital, 1-172 Hokke, Nakagawa-Ku, Nagoya-Shi, Aichi, 454-0933, Japan.
Kenichi KonoDepartment of Physical Therapy, School of Health Sciences at Narita, International University of Health and Welfare, 4-3, Kozunomori, Narita-Shi, Chiba, 286-8686, Japan.
Yuto ImotoDepartment of Rehabilitation, Nagoya Kyoritsu Hospital, 1-172 Hokke, Nakagawa-Ku, Nagoya-Shi, Aichi, 454-0933, Japan.
Ayaka OnoyamaDepartment of Rehabilitation, Nagoya Kyoritsu Hospital, 1-172 Hokke, Nakagawa-Ku, Nagoya-Shi, Aichi, 454-0933, Japan.
Sayaka ItoDepartment of Rehabilitation, Nagoya Kyoritsu Hospital, 1-172 Hokke, Nakagawa-Ku, Nagoya-Shi, Aichi, 454-0933, Japan.
Yoshifumi MoriyamaDepartment of Wellness Center, Nagoya Kyoritsu Hospital, 1-172 Hokke, Nakagawa-Ku, Nagoya-Shi, Aichi, 454-0933, Japan.
Hirotake KasugaDepartment of Nephrology, Nagoya Kyoritsu Hospital, 1-172 Hokke, Nakagawa-Ku, Nagoya-Shi, Aichi, 454-0933, Japan.
Yasuhiko ItoDepartment of Nephrology and Rheumatology, Aichi Medical University, 1-1 Karimata, Yazako, Nagakute, 480-1195, Japan.
Nagoya Kyouritsu Hospital · JPAichi Medical University · JPInternational University of Health and Welfare · JPSeirei Christopher University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow physical function and malnutrition in elderly patients undergoing peritoneal dialysis (PD) are important issues that may be associated with prognosis. We aimed to determine the association between physical function and nutritional status and survival in elderly patients undergoing PD.

methodsThis single-center, prospective cohort study included 45 stable, ambulatory patients undergoing PD. Physical function was measured using the 6-min walk distance (6MWD) test, 10-m walk speed, handgrip strength, lower extremity muscle strength, and short physical performance battery. Nutritional status was assessed using albumin levels and the Geriatric Nutritional Risk Index (GNRI). Patients were divided into two groups according to adverse events. Receiver operating characteristic curve analysis was used to predict mortality. The relationships between all-cause mortality and physical function and nutritional status were studied using Kaplan-Meier analysis and the log-rank test.

resultsThe mean patient age was 75.3 ± 6.5 years. The median follow-up time was 32 (interquartile range 18-51) months, during which 11 deaths occurred. Death during follow-up was significantly associated with lower 6MWD (237.4 ± 120.2 vs. 355.2 ± 105.9 m), lower GNRI (77.3 ± 16.3 vs. 89.3 ± 8.1), and lower albumin levels (2.8 ± 0.6 vs. 3.3 ± 0.4 mg/dL) at baseline (p < 0.05). The cut-off values were 338 m, 83.3, and 2.95 g/dL for the 6MWD, GNRI, and albumin levels, respectively. The 6MWD test, GNRI, and albumin levels were significantly associated with all-cause mortality (p < 0.05). Additionally, the group with combined exercise intolerance and malnutrition had a lower survival rate (p < 0.05).

conclusionLower 6MWD and malnutrition are predictors of mortality in elderly patients undergoing PD.

Indexed as

MalnutritionPeritoneal DialysisAgedAged, 80 and overAlbuminsGeriatric AssessmentHand StrengthHumansNutritional StatusNutrition AssessmentProspective StudiesRisk FactorsAlbumins6-min walk distanceGeriatric nutritional risk indexPeritoneal dialysis

Identifiers

PMID36562903
OpenAlexW4312114604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.