Evidence map›Paper›PMID 36562833›Full record

Trial reportEuropean journal of pediatrics2023

Ultrasound-guided reduction of intussusception in infants in a developing world: saline hydrostatic or pneumatic technique?

Isaac S Chukwu, Sebastian O Ekenze, Uchechukwu O Ezomike, Kevin E Chukwubuike, Samuel C Ekpemo

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Isaac S ChukwuSub-Department of Pediatric Surgery, University of Nigeria Teaching Hospital Ituku/Ozalla, Enugu, Nigeria. Isaacchukwu8@gmail.com.
Sebastian O EkenzeSub-Department of Pediatric Surgery, University of Nigeria Teaching Hospital Ituku/Ozalla, Enugu, Nigeria.
Uchechukwu O EzomikeSub-Department of Pediatric Surgery, University of Nigeria Teaching Hospital Ituku/Ozalla, Enugu, Nigeria.
Kevin E ChukwubuikeDepartment of Surgery, Enugu State University Teaching Hospital, Parklane, Enugu, Nigeria.
Samuel C EkpemoDepartment of Surgery, Federal Medical Centre, Umuahia, Nigeria.
University of Nigeria Teaching Hospital · NGEnugu State University of Science and Technology · NGFederal Medical Centre · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-operative reduction has emerged as first line in the management of uncomplicated intussusception. The aim of this study was to compare the outcome of ultrasound-guided saline hydrostatic reduction and ultrasound-guided pneumatic reduction of intussusception in infants. This is a prospective study of infants with uncomplicated intussusception confirmed by ultrasound over a period of 21 months from December 2018 to August 2020. Fifty-two (69.3%) out of seventy-five infants were eligible and randomized based on simple random sampling technique into two groups: Group A included patients who had ultrasound-guided hydrostatic (saline) reduction; Group B included patients who had ultrasound-guided pneumatic (air) reduction. The success rates, time to reduction and complication rates were assessed. The success rates, between the saline hydrostatic reduction group and pneumatic reduction group, were comparable [17 (65.4%) versus 19 (73.1%); relative risk (RR) 0.8; 95% confidence interval (CI) 0.6-1.2; p = 0.54]. The mean time to reduction was higher in the saline hydrostatic reduction group (15.4 ± 5.1 min versus 10.8 ± 4.1 min; p = 0.003). There was no statistically significant difference in the perforation and recurrence rates between the two groups.

conclusionSaline hydrostatic reduction and pneumatic reduction of uncomplicated intussusception under ultrasound guidance in infants might have comparable outcomes. However, pneumatic reduction may be faster. WHAT IS KNOWN: • Ileocolic intussusception is the most common cause of intestinal obstruction in infants. • Ultrasonography is useful in the diagnosis and non-operative treatment of ileocolic intussusception. WHAT IS NEW: • Ultrasound-guided hydrostatic enema and ultrasound-guided pneumatic enema are similarly effective and safe techniques in the reduction of ileocolic intussusception. • Reduction of ileocolic intussusception under ultrasound guidance is a great technique that may prove useful in the developing world due to lower cost of required equipment.

Indexed as

IntussusceptionEnemaHumansHydrostatic PressureInfantProspective StudiesTreatment OutcomeUltrasonographyUltrasonography, InterventionalDeveloping worldHydrostatic reductionInfantsIntussusceptionOutcomePneumatic reduction

Identifiers

PMID36562833
OpenAlexW4312115207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.