Evidence map›Paper›PMID 36562782›Full record

ArticleEuropean radiology2023

Prediction of cardiovascular events using myocardial strain ratio derived from

Atsushi Yamamoto, Michinobu Nagao, Masateru Kawakubo, Kiyoe Ando, Risako Nakao, Yuka Matsuo, Akiko Sakai, Koichiro Kaneko, Mitsuru Momose, Shuji Sakai and 1 more

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Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Atsushi YamamotoDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Michinobu NagaoDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan. nagao.michinobu@twmu.ac.jp.ORCID http://orcid.org/0000-0001-6049-8857
Masateru KawakuboDepartment of Health Sciences, Faculty of Medical Science, Kyushu University, Fukuoka, Japan.
Kiyoe AndoDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Risako NakaoDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Yuka MatsuoDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan.
Akiko SakaiDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Koichiro KanekoDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan.
Mitsuru MomoseDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan.
Shuji SakaiDepartment of Diagnostic Imaging and Nuclear Medicine, Tokyo Women's Medical University, 8-1, Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan.
Junichi YamaguchiDepartment of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMyocardial flow reserve (MFR), derived from ammonia N-13 positron emission tomography (NH

methodsNinety-five patients underwent NH

resultsThe ROC curve analysis demonstrated a cutoff of 0.93 for MACE with MSR (sensitivity and specificity of 77% and 71%, respectively). Patients with MSR < 0.93 displayed a significantly higher MACE rate than those with MSR ≥ 0.93 (p = 0.0036). The Cox proportional hazards regression analysis indicated that MSR was an independent marker that could predict MACE in imaging and clinical parameters (HR, 7.32; 95% CI: 1.59-33.7, p = 0.011).

conclusionsMSR was an independent predictor of MACE and was useful for further risk stratification in IHD. MSR has the potential for a new indicator of revascularization in patients with IHD. KEY POINTS: • We hypothesized that combining myocardial flow reserve (MFR) with the myocardial strain ratio (MSR) obtained by applying the feature-tracking technique to ammonia N-13 PET would make it predictive of major adverse cardiac events (MACE) compared to MFR alone. • MSR was an independent predictor of MACE, allowing for further risk stratification in addition to MFR in patients with ischemic heart disease. • MSR is a potential new indicator of revascularization.

Indexed as

Coronary Artery DiseaseFractional Flow Reserve, MyocardialHeart FailureMyocardial IschemiaMyocardial Perfusion ImagingAmmoniaHumansMyocardiumPositron-Emission TomographyPrognosisRadiopharmaceuticalsAmmoniaRadiopharmaceuticals13N-ammonia positron emission tomographyIschemic heart diseaseMyocardial flow reserveMyocardial strain ratioPrognosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.