ArticleACS applied materials & interfaces2023
Acceleration of Oral Wound Healing under Diabetes Mellitus Conditions Using Bioadhesive Hydrogel.
Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 70 citations in OpenAlex.
- Adhesive Hydrogel Loaded with Sulfonated Chitosan Promotes Oral Mucosal Defect Repair in Diabetic Rats.Bioengineering (Basel, Switzerland) · 2026Article
- Octopus sucker-inspired, Turkish gall extract-integrated microneedle patch for oral ulcer mitigation.iScience · 2026Article
- Oral microalgal nanoparticle hydrogel for multifaceted management of chronic oral ulcers in diabetes.Journal of nanobiotechnology · 2026Article
- Targeted repair of oral mucosal injury: emerging applications of biomaterials-based drug delivery systems.Journal of nanobiotechnology · 2026Review
- Hierarchically assembled curcumin-vitamin E-zinc thermo-gel for multi-synergistic prevention and treatment of radiation-induced oral mucositis.Materials today. Bio · 2025Article
- Fibroblast Dysfunction and Immune Dysregulation Impair Palatal Wound Healing in Diabetic Rats.International dental journal · 2025Article
- Distinct Molecular Mechanisms in Oral Mucosal Wound Healing: Translational Insights and Future Directions.International journal of molecular sciences · 2025Review
- Hydrogel Loaded with Aminoethyl Anisamide-Modified Exosomes Attenuates Hepatic Fibrosis by Targeting Activated Hepatic Stellate Cells.ACS nano · 2025Article
- Poly (hydroxyethyl methacrylate) Saliva-Gel: A Polymer-Based Solution for Xerostomia Treatment.ACS applied polymer materials · 2025Article
- Role of chemistry in nature-inspired skin adhesives.Chemical science · 2025Review
- Electrical Microneedles for Wound Treatment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- A machine learning-based risk prediction model for diabetic oral ulceration.BMC oral health · 2025Article
- Radiation-Therapy Related Salivary Dysfunction.Seminars in radiation oncology · 2025Review
- MXene-Integrated Responsive Hydrogel Microneedles for Oral Ulcers Healing.Smart medicine · 2025Article
- Hydrogels in Oral Disease Management: A Review of Innovations in Drug Delivery and Tissue Regeneration.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Internal-External Homologous Drug-Loaded Exosome-Like Nanovesicles Released from Semi-IPN Hydrogel Enhancing Wound Healing of Chemoradiotherapy-Induced Oral Mucositis.International journal of nanomedicine · 2025Article
- The Extracellular Matrix Promotes Diabetic Oral Wound Healing by Modulating the Microenvironment.Biomaterials research · 2025Article
- Emerging novel hydrogels application in oral and gastrointestinal diseases: design wet adhesive strategy towards possible mechanisms.Science and technology of advanced materials · 2025Review
- Hierarchical Micro/Nano-Structured Biomaterials for Wound Healing.Research (Washington, D.C.) · 2025Review
- Advances in smart stimuli-responsive materials for oral wound healing.Frontiers in chemistry · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral wounds under diabetic conditions display a significant delay during the healing process, mainly due to oxidative stress-induced inflammatory status and abnormal immune responses. Besides, the wet and complicated dynamic environment of the oral cavity impedes stable treatment of oral wounds. To overcome these, a biomimetic hydrogel adhesive was innovatively developed based on a mussel-inspired multifunctional structure. The adhesive displays efficient adhesion and mechanical harmony on the oral mucosa through enhanced bonding in an acidic proinflammatory environment. The bioadhesive hydrogel exhibits excellent antioxidative properties by mimicking antioxidative enzymatic activities to reverse reactive oxygen species (ROS)-mediated immune disorders. Experiments on oral wounds of diabetic rats showed that this hydrogel adhesive could effectively protect against mucosal wounds and obviously shorten the inflammatory phase, thus promoting the wound-healing process. Therefore, this study offers a promising therapeutic choice with the potential to advance the clinical treatment of diabetic oral wounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.