Evidence map›Paper›PMID 36562290›Full record

ArticleDevelopment and psychopathology2024

Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study.

Hayley Guiney, Avshalom Caspi, Antony Ambler, Jay Belsky, Jesse Kokaua, Jonathan Broadbent, Kirsten Cheyne, Nigel Dickson, Robert J Hancox, HonaLee Harrington and 6 more

Abstract read
In one paragraph

Article in Development and psychopathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  10. Harmful sexual behaviours against siblings in New Zealand: could assessment of the family environment guide therapeutic intervention?Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hayley GuineyDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.ORCID 0000-0003-1311-8625
Avshalom CaspiDepartment of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Antony AmblerDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.
Jay BelskyRobert M. and Natalie Reid Dorn Professor, Department of Human Ecology, University of California, Davis, CA, USA.
Jesse KokauaDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.
Jonathan BroadbentUniversity of Otago Faculty of Dentistry, Dunedin, New Zealand.
Kirsten CheyneDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.
Nigel DicksonDepartment of Preventive and Social Medicine, Otago Medical School, University of Otago, New Zealand.
Robert J HancoxDepartment of Preventive and Social Medicine, Otago Medical School, University of Otago, New Zealand.
HonaLee HarringtonDepartment of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Sean HoganDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.
Sandhya RamrakhaDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.
Antoinette RighartsDepartment of Preventive and Social Medicine, Otago Medical School, University of Otago, New Zealand.
W Murray ThomsonUniversity of Otago Faculty of Dentistry, Dunedin, New Zealand.
Terrie E MoffittDepartment of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Richie PoultonDunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago, Dunedin, New Zealand.

Funding

Quantifying Individual Differences in Midlife Structural Brain Integrity Associated with Later AD/ADRD RiskR01AG049789 · NIA · DUKE UNIVERSITY · PI AHMAD R. HARIRI, TERRIE E MOFFITT · 2015 to 2026
$10.6M
Is mental disorder a preventable cause of age-related disease? The Dunedin Study.R01AG032282 · NIA · DUKE UNIVERSITY · PI CASPI, AVSHALOM, MOFFITT, TERRIE E · 2009 to 2025
$9.5M
Medical Research CouncilNIA NIH HHS R01 AG032282NIA NIH HHS R01 AG049789
6 · The paper itself

Abstract

The aim of this study was to use longitudinal population-based data to examine the associations between childhood sexual abuse (CSA) and risk for adverse outcomes in multiple life domains across adulthood. In 937 individuals followed from birth to age 45y, we assessed associations between CSA (retrospectively reported at age 26y) and the experience of 22 adverse outcomes in seven domains (physical, mental, sexual, interpersonal, economic, antisocial, multi-domain) from young adulthood to midlife (26 to 45y). Analyses controlled for sex, socioeconomic status, prospectively reported child harm and household dysfunction adverse childhood experiences, and adult sexual assault, and considered different definitions of CSA. After adjusting for confounders, CSA survivors were more likely than their peers to experience internalizing, externalizing, and thought disorders, suicide attempts, health risk behaviors, systemic inflammation, poor oral health, sexually transmitted diseases, high-conflict relationships, benefit use, financial difficulties, antisocial behavior, and cumulative problems across multiple domains in adulthood. In sum, CSA was associated with multiple persistent problems across adulthood, even after adjusting for confounding life stressors, and the risk for particular problems incremented with CSA severity. The higher risk for most specific problems was small to moderate, but the cumulative long-term effects across multiple domains reflect considerable individual and societal burden.

Indexed as

Child Abuse, SexualAdolescentAdultChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMiddle AgedRetrospective StudiesSexual BehaviorSocial ClassSuicide, AttemptedYoung Adultchild sexual abuseconsequenceslongitudinallong-term outcomesmulti-morbidity

Identifiers

PMID36562290
PMCPMC10287838

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.