Evidence map›Paper›PMID 36562248›Full record

ArticleClinical and experimental dental research2023

Establishment of quantitative indicators for an efficient treatment on masticatory muscle pain.

Sunhee Lee, Hye-Min Ju, Donald Ho, Byong-Sop Song, Sung-Hee Jeong, Yong-Woo Ahn, Soo-Min Ok, Kyounga Cheon

Open access · goldAbstract read
In one paragraph

Article in Clinical and experimental dental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sunhee LeeDepartment of Oral Medicine, Dental and Life Science Institute, Pusan National University, Yangsan, Republic of Korea.
Hye-Min JuDepartment of Oral Medicine, Dental and Life Science Institute, Pusan National University, Yangsan, Republic of Korea.
Donald HoDepartment of Pediatric Dentistry, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Byong-Sop SongDepartment of Statistics, Graduate School of the Pusan National University, Busan, Republic of Korea.
Sung-Hee JeongDepartment of Oral Medicine, Dental and Life Science Institute, Pusan National University, Yangsan, Republic of Korea.
Yong-Woo AhnDepartment of Oral Medicine, Dental and Life Science Institute, Pusan National University, Yangsan, Republic of Korea.
Soo-Min OkDepartment of Oral Medicine, Dental and Life Science Institute, Pusan National University, Yangsan, Republic of Korea.ORCID 0000-0003-1776-371X
Kyounga CheonDepartment of Pediatric Dentistry, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-0629-097X
Pusan National University Dental Hospital · KRUniversity of Alabama at Birmingham · USPusan National University · KR

Funding

NITRIC OXIDE RELEASING BIOMIMETRIC NANOMATRIX GELF OR ROOT REVITALIZATIONK08DE027401 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHEON, KYOUNGA · 2017 to 2022
$798k
NIDCR NIH HHS K08 DE027401
6 · The paper itself

Abstract

backgroundAlthough several studies have investigated effective treatments for masticatory muscle pain (MMP), no unified conclusion has been drawn regarding the effectiveness of these treatments.

objectivesThis study aimed to define quantitative indicators for predicting the outcome of MMP treatment. MATERIALS AND

methodsIn total, patients aged 20-70 years were recruited and divided into the MMP (n = 24) and control (n = 36) groups, based on the presence of MMP according to the Diagnostic Criteria for Temporomandibular Disorders. At pretreatment, the MMP group was assessed using quantitative indicators such as subjective pain levels, pain duration, graded chronic pain scale (GCPS), and perceived stress scale (PSS). Salivary alpha-amylase (sAA) and interleukin-6 (IL-6) levels were analyzed. The masticatory muscle palpation score and the range of mouth opening were measured. At posttreatment, subjective pain levels, mouth opening, and treatment/medication duration were examined. The PSS and sAA levels were assessed in the control group.

resultssAA levels in the MMP group were significantly higher than those in the control group (p < .05). The masseter muscle palpation score (MPS) showed a positive correlation with IL-6 levels (ρ = 0.503, p < .05) and a negative correlation with nonsteroidal anti-inflammatory drug (NSAID) treatment period (ρ = -0.462, p < .05). The temporalis muscle palpation score (TPS) was positively correlated with pain duration and GCPS grade (ρ = 0.483, p < .05, and ρ = 0.445, p < .05, respectively).

conclusionsTreatment with NSAIDs was effective in the MMP group with high MPS and IL-6 levels, but not in the MMP group with high TPS, pain duration, and GCPS grade.

Indexed as

Masseter MuscleTemporomandibular Joint DisordersHumansInterleukin-6PainTemporal MuscleInterleukin-6differential diagnosisindividualized treatmentmasticatory muscle paintemporomandibular joint disorder

Identifiers

PMID36562248
PMCPMC9932258
OpenAlexW4312112857

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.