SynthesisFrontiers in nutrition2022
Malnutrition diagnosed by the Global Leadership Initiative on Malnutrition criteria predicting survival and clinical outcomes of patients with cancer: A systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Global epidemiological characteristics of malnutrition in cancer patients: a comprehensive meta-analysis and systematic review.BMC cancer · 2025Pooled it
- Association between malnutrition diagnosed by different screening and assessment tools and clinical outcomes: an umbrella review.Frontiers in nutrition · 2025Pooled it
- Article
- Effects of Malnutrition on In-Hospital and Discharge Outcomes Among Young Adults Hospitalized with Gastrointestinal Cancers: National Estimates from the United States.Journal of gastrointestinal cancer · 2026Article
- Association between nutritional status, chemotherapy cycle count and treatment responses in adults with cancer in Ethiopia: a prospective cohort study.BMJ nutrition, prevention & health · 2026Article
- Prognostic impact of glim-defined malnutrition and phase angle in patients with digestive tumors.Frontiers in nutrition · 2026Article
- Undernutrition and associated factors among adult cancer patients in northwest Ethiopia: a global leadership initiative on malnutrition-based approach.BMC cancer · 2025Article
- GLIM consensus approach to diagnosis of malnutrition: A 5-year update.JPEN. Journal of parenteral and enteral nutrition · 2025Review
- Prognostic value of the CIPA nutritional screening tool in over 30,000 hospitalized patients: a retrospective study (2014-2022).Frontiers in nutrition · 2025Article
- A scoping review of diet and exercise interventions for older cancer survivors' physical function.Journal of geriatric oncology · 2024Article
- Global Leadership Initiative on Malnutrition-defined malnutrition coexisting with visceral adiposity predicted worse long-term all-cause mortality among inpatients with decompensated cirrhosis.Nutrition & diabetes · 2024Article
- Nutritional Assessment Tools for Patients with Cancer: A Narrative Review.Current medical science · 2024Review
- Validation of the Global Leadership Initiative on Malnutrition Criteria for Predicting Adverse Outcomes in Acute Pancreatitis.Therapeutics and clinical risk management · 2024Article
- Comparative Study of Different Inflammation Definition Methods of GLIM in the Diagnosis of Malnutrition in Patients with Acute Pancreatitis.International journal of general medicine · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Recently, some cohorts have looked into the use of Global Leadership Initiative on Malnutrition (GLIM) criteria in cancer patients. The objective of the current meta-analysis was to determine its utility in predicting clinical and survival outcomes for cancer patients. Method: Searching and screening literature from PubMed, Web of Science and Embase until September 13, 2022 was performed by two researchers independently. According to the exclusion and inclusion criteria, articles reporting the impact of malnutrition diagnosed by GLIM on long-term survival and clinical outcomes were included. Data of interest were also extracted from the included papers. The stability of the pooled results was evaluated using sensitivity analysis. With the aid of subgroup analysis, heterogeneity was revealed. To assess publication bias, Egger's and Begg's tests were conducted. The influence of publication bias on the pooling risk estimate was examined using a trim-and-fill analysis. Results: 15 studies that qualified for our study were identified. Pooled hazard ratio (HR) from both multivariate and univariate regression analysis showed a worse overall survival in GLIM-defined malnourished cancer patients than those in well-nourished status. Meanwhile, disease-free survival was also poorer in malnourished patients. Moreover, pooled odds ratio (OR) demonstrated that malnourished cancer patients were more likely to develop overall postoperative complications, complications ≥ Clavien-Dindo grade IIa and complications ≥ Clavien-Dindo grade IIIa. Two articles reported negative relation between GLIM-defined malnutrition and 30-day readmission/mortality. Conclusion: GLIM-defined malnutrition possesses value in predicting poorer survival and clinical outcomes for cancer patients. Systematic review registration: [https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=321094], identifier [CRD42022321094].
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