ArticlePublic health action2022
Caregivers' perspectives on health-related quality of life in young children with TB and respiratory illnesses.
Article in Public health action, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Proceedings from the Third International Post-Tuberculosis Symposium: expanding the circle.IJTLD open · 2025Article
- Post-TB treatment completion experiences of children, adolescents, and caregivers from Cape Town.IJTLD open · 2025Article
- Lung life HRQoL measure: psychometric properties and initial data in presumptive TB.IJTLD open · 2025Article
- Burden and determinants of MDR-TB among prisoners in sub-Saharan Africa: Systematic review and meta-analysis protocol.Journal of public health in Africa · 2025Article
- Article
- Health-related quality of life in children with presumptive TB.IJTLD open · 2024Article
- An item bank to measure health-related quality of life among young children (0-5-years-old) affected by respiratory illnesses - expert stakeholders and end-users from the Western Cape, South Africa.Health and quality of life outcomes · 2024Article
- A scoping review of interventions to address TB associated respiratory disability.EClinicalMedicine · 2024Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThere is a lack of holistic health-related quality of life (HRQoL) measures for young children with respiratory disease, especially in low- and middle-income countries (LMICs). We aimed to understand caregivers' perceptions of the relevance of common HRQoL domains for children with respiratory diseases, including TB.
methodsThis study was nested in a prospective observational cohort of children presenting with respiratory symptoms presumptive of pulmonary TB. We conducted 10 semi-structured interviews to explore caregivers' perceptions of the five commonly measured HRQoL domains: physical health, social support, emotional and psychological wellbeing, and schooling. We used case descriptive analysis and thematic coding.
resultsCaregivers considered all five domains to be relevant. The socio-economic context framed their responses, with QoL requiring sufficient basic resources for children. HRQoL experiences varied according to the severity of the child's symptoms, but not between TB and non-TB illnesses. Manifestations in the psychological domain were difficult to distinguish from the emotional domain. Social support included broad support for family members, indirectly benefiting the children. Caregivers were concerned about their children's early developmental milestones and future schooling.
conclusionThis exploratory study shows that HRQoL domains are relevant but require adaptation to be applicable for young children affected by respiratory illnesses living in LMICs.
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