Evidence map›Paper›PMID 36561844›Full record

ArticleOpen medicine (Warsaw, Poland)2022

Integrated bioinformatics analysis shows integrin alpha 3 is a prognostic biomarker for pancreatic cancer.

Fangfang Hu, Liangtao Zhao, Yang Wang, Hao Ye, Haodong Tang, Jiahua Zhou

Abstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
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  5. Article
  6. Autologous profiling reveals inter-patient heterogeneity in Vδ2Journal for immunotherapy of cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fangfang HuDepartment of Hepatobiliary and Pancreatic Surgery, Zhongda Hospital Affiliated to Southeast University, Nanjing, 210009, China.
Liangtao ZhaoDepartment of Hepatobiliary and Pancreatic Surgery, Zhongda Hospital Affiliated to Southeast University, Nanjing, 210009, China.
Yang WangDepartment of Hepatobiliary and Pancreatic Surgery, Zhongda Hospital Affiliated to Southeast University, Nanjing, 210009, China.
Hao YeSchool of Medicine, Southeast University, Nanjing, 210009, China.
Haodong TangSchool of Medicine, Southeast University, Nanjing, 210009, China.
Jiahua ZhouDepartment of Hepatobiliary and Pancreatic Surgery, Zhongda Hospital Affiliated to Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing, 210009, China.ORCID https://orcid.org/0000-0003-0551-5604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrin subunit alpha 3 (ITGA3) expression correlates with the development and prognosis of human cancers. This study aimed to investigate the association of ITGA3 expression with pancreatic cancer (PCa) prognosis. The ITGA3 gene expression data were extracted from The Cancer Genome Atlas (TCGA) pancreatic adenocarcinoma (PAAD) cohort and 14 Gene Expression Omnibus microarray datasets. The differences in ITGA3 expression levels between tumor and non-tumor tissues were compared using the Mann-Whitney

Indexed as

extracellular matrixintegrin alpha 3meta-analysispancreatic cancerPI3K-Akt signaling pathway

Identifiers

PMID36561844
PMCPMC9743194

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.