Evidence map›Paper›PMID 36561522›Full record

ReviewFrontiers in oncology2022

The prevention and treatment of breast cancer- related lymphedema: A review.

Maureen P McEvoy, Ameer Gomberawalla, Mark Smith, Francesco M Boccardo, Dennis Holmes, Risal Djohan, Paul Thiruchelvam, Suzanne Klimberg, Jill Dietz, Sheldon Feldman

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 4 pooled it
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Effect of eight different acupuncture and moxibustion therapies on breast cancer-related lymphedema: a Bayesian network meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  16. Advancing Lymphedema Surveillance With Evidence-Based Practices.Clinical journal of oncology nursing · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 3 countries.

Maureen P McEvoyBreast Surgery Division, Department of Surgery, Montefiore Medical Center, Montefiore Einstein Center for Cancer Care, Bronx, NY, United States.
Ameer GomberawallaDepartment of Surgery, Advocate Medical Group, Oak Lawn, IL, United States.
Mark SmithDepartment of Plastic Surgery, Northwell Health System, New Hyde Park, NY, United States.
Francesco M BoccardoDepartment of Surgery, San Martino Hospital, University of Genoa, Genova, Italy.
Dennis HolmesDepartment of Surgery, Los Angeles Center for Women's Health, Los Angeles, CA, United States.
Risal DjohanDepartment of Plastic Surgery, Cleveland Clinic, Cleveland, OH, United States.
Paul ThiruchelvamDepartment of Breast Surgery, Imperial College, London, United Kingdom.
Suzanne KlimbergDepartment of Surgery, University of Texas Medical Branch(UTMB) Cancer Center, Galveston, TX, United States.
Jill DietzDepartment of Surgery, University Hospital Cleveland Medical Center, Cleveland, OH, United States.
Sheldon FeldmanBreast Surgery Division, Department of Surgery, Montefiore Medical Center, Montefiore Einstein Center for Cancer Care, Bronx, NY, United States.
Albert Einstein College of Medicine · USAlcoholism Center for Women · USCleveland Clinic · USImperial College London · GBMontefiore Medical Center · USNorthwell Health · USOspedale Policlinico San Martino · ITThe University of Texas Medical Branch at Galveston · USUniversity Hospitals of Cleveland · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Breast cancer- related lymphedema (BCRL) affects about 3 to 5 million patients worldwide, with about 20,000 per year in the United States. As breast cancer mortality is declining due to improved diagnostics and treatments, the long-term effects of treatment for BCRL need to be addressed. Methods: The American Society of Breast Surgeons Lymphatic Surgery Working Group conducted a large review of the literature in order to develop guidelines on BCRL prevention and treatment. This was a comprehensive but not systematic review of the literature. This was inclusive of recent randomized controlled trials, meta-analyses, and reviews evaluating the prevention and treatment of BCRL. There were 25 randomized clinical trials, 13 systemic reviews and meta-analyses, and 87 observational studies included. Results: The findings of our review are detailed in the paper, with each guideline being analyzed with the most recent data that the group found evidence of to suggest these recommendations. Conclusions: Prevention and treatment of BCRL involve a multidisciplinary team. Early detection, before clinically apparent, is crucial to prevent irreversible lymphedema. Awareness of risk factors and appropriate practice adjustments to reduce the risk aids are crucial to decrease the progression of lymphedema. The treatment can be costly, time- consuming, and not always effective, and therefore, the overall goal should be prevention.

Indexed as

axillary reverse mappingaxillary surgerybreast cancerbreast cancer related lymphedemaLyMPHAlymphedema

Identifiers

PMID36561522
PMCPMC9763870
OpenAlexW4311633551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.