Evidence map›Paper›PMID 36561401›Full record

ArticleJournal of cutaneous and aesthetic surgery

Use of Cultivated Epidermal Allograft in Chronic Wounds: A Novel Therapeutic Alternative.

Daniel De-Luna-Gallardo, Alberto I Cahuana-Quispe, Jaime A García-Espinoza, Blanca Y Arámbula-Sánchez, Carlos I Navarro-Delgadillo, Rodrigo Dávila-Díaz, Mauricio A Erazo-Franco, Alejandro Costa-Dulche, Ana A Mena-Garza, Rodrigo Morales-De-La-Cerda and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of cutaneous and aesthetic surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Daniel De-Luna-GallardoPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Alberto I Cahuana-QuispePlastic and Reconstructive Surgery, Hospital Central Norte de Petroleos Mexicanos, Mexico City, Mexico.
Jaime A García-EspinozaPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Blanca Y Arámbula-SánchezPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Carlos I Navarro-DelgadilloPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Rodrigo Dávila-DíazPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Mauricio A Erazo-FrancoPlastic and Reconstructive Surgery, The American British Cawdray Center, Mexico City, Mexico.
Alejandro Costa-DulchePlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Ana A Mena-GarzaPlastic and Reconstructive Surgery, The American British Cawdray Center, Mexico City, Mexico.
Rodrigo Morales-De-La-CerdaPlastic and Reconstructive Surgery, The American British Cawdray Center, Mexico City, Mexico.
David Flores-SotoPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Marco A Cuervo-VergaraPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Patricia Alma Reyes-IbarraPlastic and Reconstructive Surgery, The American British Cawdray Center, Mexico City, Mexico.
Cuahutémoc Márquez-EsrpiellaPlastic and Reconstructive Surgery, Hospital Central Sur de Alta Especialdiad de Petroleos Mexicanos, Mexico City, Mexico.
Pemex (Mexico) · MXCentro Médico ABC · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic wounds represent a frequent cause of consultation for plastic and reconstructive surgeons. The use of epidermal culture stands out because they provide complete epithelialization, adequate aesthetic-functional results, and no morbidity for the patient. Epifast® is a pre-manufactured cultured epidermal allograft derived from the amplification Materials and Methods: A prospective longitudinal multicenter study was carried out in four chronic wound reference centers, which were in charge of plastic and reconstructive surgery services. For a standardized wound bed preparation, the protocol synthesized by the acronym "TIME" was used. At the end of the "TIME" protocol, the pre-fabricated allograft was applied and removed 7 days after its application. Results: A total of 133 patients with diagnosis of chronic wound were included in the study. The median age was 69.3 ± 13.6 years. The most common comorbidity found was diabetes mellitus type 2 in 71.4% of the patients ( Conclusion: Cultured epidermal allograft, combined with a meticulous technique and an adequate selection of patients, represents a safe and effective tool for chronic wounds.

Indexed as

Allograftschronic woundcultured epidermal graftsepidermal substitutesEpifastMexicoplastic surgeryreconstructive surgery

Identifiers

PMID36561401
PMCPMC9764952
OpenAlexW4312129683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.