Evidence map›Paper›PMID 36561310›Full record

ArticleFrontiers in genetics2022

Transcriptomic changes underlying glucocorticoid-induced suppression of milk production by dairy cows.

Anna Sadovnikova, Sergio C Garcia, Josephine F Trott, Alice T Mathews, Monica T Britton, Blythe P Durbin-Johnson, Russell C Hovey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna SadovnikovaDepartment of Animal Science, University of California, Davis, Davis, CA, United States.
Sergio C GarciaSchool of Life and Environmental Sciences, University of Sydney, Sydney, NSW, Australia.
Josephine F TrottDepartment of Animal Science, University of California, Davis, Davis, CA, United States.
Alice T MathewsDepartment of Animal Science, University of California, Davis, Davis, CA, United States.
Monica T BrittonUC Davis Bioinformatics Core, University of California, Davis, Davis, CA, United States.
Blythe P Durbin-JohnsonUC Davis Bioinformatics Core, University of California, Davis, Davis, CA, United States.
Russell C HoveyDepartment of Animal Science, University of California, Davis, Davis, CA, United States.

Funding

UC Davis CTSC TL1 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility MentorshipTL1TR001861 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MEDICI, VALENTINA · 2016 to 2025
$4.7M
NCATS NIH HHS TL1 TR001861
6 · The paper itself

Abstract

Milk production by dairy cows is sensitive to increased levels of stress hormones such as glucocorticoids (GC) that also regulate the transcription of several genes required for milk synthesis. Whereas previous studies identified that an exogenous GC such as dexamethasone (DEX) transiently suppresses milk yield in several species without any pronounced effect on milk protein or fat percentage, the mechanism underlying this effect has not been established. In this study we sought to establish changes within the mammary glands of non-pregnant dairy cows in their second lactation (

Indexed as

alpha-lactalbumindexamethasoneinflammationlactationlactose

Identifiers

PMID36561310
PMCPMC9763454

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.