Evidence map›Paper›PMID 36561128›Full record

ArticleJHEP reports : innovation in hepatology2023

Comparison of radiofrequency ablation and ablative external radiotherapy for the treatment of intrahepatic malignancies: A hybrid meta-analysis.

Chai Hong Rim, Jung Sue Lee, Soo Yeon Kim, Jinsil Seong

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JHEP reports : innovation in hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

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  11. Do We Have a Winner? Advocating for SBRT in HCC Management.Clinical and translational radiation oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chai Hong RimDepartment of Radiation Oncology, Korea University Medical College, Seoul, South Korea.
Jung Sue LeeKorea University Medical College, Seoul, South Korea.
Soo Yeon KimKorea University Medical College, Seoul, South Korea.
Jinsil SeongDepartment of Radiation Oncology, Yonsei Cancer Center, Seoul, South Korea.
Korea University Medical Center · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & Aims: Radiofrequency ablation (RFA) and ablative external beam radiotherapy (ablative RT) are commonly used to treat small intrahepatic malignancies. We meta-analysed oncologic outcomes and systematically reviewed the clinical consideration of tumour location and size. Methods: PubMed, Medline, Embase, and Cochrane Library databases were searched on February 24, 2022. Studies comparing RFA and ablative RT, providing one of the endpoints (local control or survival), and encompassing ≥5 patients in each arm were included. Results: Twenty-one studies involving 4,638 patients were included. Regarding survival, the odds ratio (OR) was 1.204 ( Conclusions: Our study shows that ablative RT can yield oncologic outcomes similar to RFA, and suggests that it can be more effective for the treatment of tumours in locations where RFA is difficult to perform or for large-sized tumours. Systematic Review Registration: This study was registered with PROSPERO (Protocol No: CRD42022332997). Impact and implications: Radiofrequency ablation (RFA) and ablative radiotherapy (RT) are non-surgical modalities for the treatment of small intrahepatic malignancies. Ablative RT showed oncologic outcomes at least similar to those of RFA, and was more effective at specific locations (

Indexed as

ASCO, American Society of Clinical OncologyASTRO, American Society for Radiation OncologyCIRSE, cardiovascular and interventional radiological society of EuropeCRC, colorectal cancerEBRT, external beam radiation therapyEQD2, Equivalent dose, 2 Gy per FractionExternal beam radiation therapyHCC, hepatocellular carcinomaHFRT, hypofractionated radiotherapyIntrahepatic malignancyIPTW, inverse probability of treatment weightingLC, local controlLiver cancerLT, liver transplantationMWA, microwave ablationNCDB, national cancer databaseOS, overall survivalPBT, proton beam therapyP, prospectivePRISMA, Preferred Reporting Items for Systematic Reviews and Meta-AnalysesPSM, propensity score matchingRadiofrequency ablationRCT, randomised controlled trialRFA, radiofrequency ablationR, retrospectiveRT, radiotherapySBRT, stereotactic body radiotherapyTACE, transarterial chemoembolisation

Identifiers

PMID36561128
PMCPMC9763860
OpenAlexW4296628539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.