ArticleJournal of geriatric cardiology : JGC2022
Systemic inflammatory markers in elderly patients undergoing transcatheter aortic valve replacement.
Article in Journal of geriatric cardiology : JGC, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 2 citations in OpenAlex.
- Association of the CALLY Index With 30-Day Outcomes After Transcatheter Aortic Valve Replacement.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- An explainable machine learning model for type B aortic dissection identification: development and internal evaluation.Frontiers in public health · 2026Article
- Prognostic value of the C-reactive protein-albumin-lymphocyte index for postoperative visual hallucinations following cardiac surgery.Frontiers in psychiatry · 2026Article
- Triglyceride-glucose index predicts early, short-term, and long-term mortality after transcatheter aortic valve replacement.American heart journal plus : cardiology research and practice · 2026Article
- Troponin at presentation: A key predictor of chronic myocardial impairment post-myocarditis-A prospective cohort study.JRSM cardiovascular diseaseArticle
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranscatheter aortic valve replacement (TAVR) provokes an early injury response, partially represented by dynamic changes in inflammatory markers. TAVR greatly benefits the elderly and we aimed to determine whether increased inflammatory markers post-TAVR in octagenerians were different than their younger counterparts and whether it was associated with adverse clinical outcomes.
methodsPatients with severe symptomatic aortic stenosis who underwent transfemoral TAVR from January 2010 to December 2021 were enrolled. Total white blood cells (WBC) count and subpopulation dynamics were evaluated.
resultsFive-hundred and seven patients were finally included in the study, 65% of these patients were 80 or more years old (54% female, median age 84 [82-87]) years, with severe symptomatic aortic stenosis. In patients aged above 80 years (patients ≥ 80), we noticed significant kinetic changes in the WBC and their differential cellular subpopulations (
conclusionThis is the first description of a differential age-related inflammatory response in patients after TAVR, which shows an association between inflammatory markers post procedure and clinical outcome. Nevertheless, survival rates were similar in the elderly population and in younger patients, despite the presence of comorbid conditions.
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Registered trials
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