Evidence map›Paper›PMID 36561042›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Miao Du, Zhuru Hou, Ling Liu, Yan Xuan, Xiaocong Chen, Lei Fan, Zhuoxi Li, Benjin Xu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Ultrafiltered Mulberry (Foods (Basel, Switzerland) · 2026
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Concentrated Polymer Brush-Modified Magnetic Particles for a Diagnostic Immunoassay.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Miao DuDepartment of Medical Laboratory Science, Fenyang College, Shanxi Medical University, Fenyang, China.
Zhuru HouScience and Technology Centre, Fenyang College of Shanxi Medical University, Fenyang, China.
Ling LiuDepartment of Medical Laboratory Science, Fenyang College, Shanxi Medical University, Fenyang, China.
Yan XuanDepartment of Medical Laboratory Science, Fenyang College, Shanxi Medical University, Fenyang, China.
Xiaocong ChenDepartment of Basic Medicine, Fenyang College of Shanxi Medical University, Fenyang, China.
Lei FanDepartment of Basic Medicine, Fenyang College of Shanxi Medical University, Fenyang, China.
Zhuoxi LiDepartment of Basic Medicine, Fenyang College of Shanxi Medical University, Fenyang, China.
Benjin XuDepartment of Medical Laboratory Science, Fenyang College, Shanxi Medical University, Fenyang, China.
Shanxi Fenyang Hospital · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein is one of the most important biological macromolecules in life, which plays a vital role in cell growth, development, movement, heredity, reproduction and other life activities. High quality isolation and purification is an essential step in the study of the structure and function of target proteins. Therefore, the development of protein purification technologies has great theoretical and practical significance in exploring the laws of life activities and guiding production practice. Up to now, there is no forthcoming method to extract any proteins from a complex system, and the field of protein purification still faces significant opportunities and challenges. Conventional protein purification generally includes three steps: pretreatment, rough fractionation, and fine fractionation. Each of the steps will significantly affect the purity, yield and the activity of target proteins. The present review focuses on the principle and process of protein purification, recent advances, and the applications of these technologies in the life and health industry as well as their far-reaching impact, so as to promote the research of protein structure and function, drug development and precision medicine, and bring new insights to researchers in related fields.

Indexed as

affinity chromatographychallenges and prospectslife and health industryprotein purificationultracentrifugation

Identifiers

PMID36561042
PMCPMC9763899
OpenAlexW4311633566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.