ArticleAnnals of Indian Academy of Neurology
Diabetic Amyotrophy (Bruns-Garland Syndrome): A Narrative Review.
Article in Annals of Indian Academy of Neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Muscle Wasting in Diabetes: A Case Report Evaluating a Rare Neuropathic Complication of Diabetic Microvasculitis.Cureus · 2026Article
- Neurological complications associated with rapid weight loss and nutritional deficiencies following GLP-1 agonist use: a case report.BMC neurology · 2025Article
- Chronic inflammatory demyelinating polyneuropathy in end-stage renal disease patients: a case series study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- A Rare Atypical Presentation of Bruns-Garland Syndrome: A Case Report and Review of Pathophysiology and Management.Cureus · 2025Article
- Diabetes Myonecrosis: A Debilitating Complication in an Indigenous Young Woman With Long Standing Type 1 Diabetes Mellitus.Case reports in endocrinology · 2024Article
- A Rare Complication of Diabetes Mellitus: Bruns-Garland Syndrome (Diabetic Amyotrophy).Journal of clinical practice and research · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
Background and Aims: Bruns-Garland syndrome (BGS) continues to be a contentious topic even 100 years after its discovery. Its lifelong incidence is 1% amongst diabetic individuals and affects middle aged-elderly individuals with type 2 diabetes mellitus (usually not poorly controlled). Methods: The data presented in this review was collated from studies published on PubMed, MEDLINE and Google Scholar in October 2021. The search words included: "Bruns-Garland syndrome", "diabetic amyotrophy" and "diabetic lumbosacral radiculoplexus neuropathy" and "proximal diabetic neuropathy". Results: The exact pathophysiology is debatable but an ischemic pathology (non-systemic microvasculitis) is most plausible. Its cardinal symptoms include acute onset of severe proximal lower extremity pain followed by weakness and wasting, some sensory loss, weight loss and autonomic symptoms. Conclusion: The prognosis is good as most patients improve to near- normal strength with pain cessation within 18 months of onset.
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